Immunomodulation by mesenchymal stem cells (MSCs): mechanisms of action of living, apoptotic, and dead MSCs

ARR Weiss, MH Dahlke - Frontiers in immunology, 2019 - frontiersin.org
Expectations on mesenchymal stem cell (MSC) treatment are high, especially in the fields of
sepsis, transplant medicine, and autoimmune diseases. Various pre-clinical studies have …

Oxidative stress and lung ischemia‐reperfusion injury

RS Ferrari, CF Andrade - Oxidative medicine and cellular …, 2015 - Wiley Online Library
Ischemia‐reperfusion (IR) injury is directly related to the formation of reactive oxygen
species (ROS), endothelial cell injury, increased vascular permeability, and the activation of …

Treatment of acute respiratory distress syndrome with allogeneic adipose-derived mesenchymal stem cells: a randomized, placebo-controlled pilot study

G Zheng, L Huang, H Tong, Q Shu, Y Hu, M Ge… - Respiratory …, 2014 - Springer
Background Recent studies have demonstrated that mesenchymal stem cells (MSCs)
modulate the immune response and reduce lung injury in animal models. Currently, no …

Exosomes from adipose-derived mesenchymal stem cells protect the myocardium against ischemia/reperfusion injury through Wnt/β-catenin signaling pathway

X Cui, Z He, Z Liang, Z Chen, H Wang… - Journal of …, 2017 - journals.lww.com
Mesenchymal stem cells (MSCs) and their secreted exosomes exert a cardioprotective role
in jeopardized myocardium. However, the specific effects and underlying mechanisms of …

Stem cell-derived and circulating exosomal microRNAs as new potential tools for diabetic nephropathy management

L Peng, Y Chen, S Shi, H Wen - Stem Cell Research & Therapy, 2022 - Springer
Background Despite major advances in the treatment of diabetic nephropathy (DN) in recent
years, it remains the most common cause of end-stage renal disease. An early diagnosis …

Adipose‐derived stem cells in tissue regeneration: a review

P Zuk - International Scholarly Research Notices, 2013 - Wiley Online Library
In 2001, researchers at the University of California, Los Angeles, described the isolation of a
new population of adult stem cells from liposuctioned adipose tissue. These stem cells, now …

Management of fibrosis: the mesenchymal stromal cells breakthrough

B Usunier, M Benderitter, R Tamarat… - Stem cells …, 2014 - Wiley Online Library
Fibrosis is the endpoint of many chronic inflammatory diseases and is defined by an
abnormal accumulation of extracellular matrix components. Despite its slow progression, it …

[HTML][HTML] Adipose-derived stem cells protect skin flaps against ischemia/reperfusion injury via IL-6 expression

CM Pu, CW Liu, CJ Liang, YH Yen, SH Chen… - Journal of Investigative …, 2017 - Elsevier
Flap necrosis is the most frequent postoperative complication encountered in reconstructive
surgery. We elucidated whether adipose-derived stem cells (ADSCs) and their derivatives …

Stem cell recruitment after injury: lessons for regenerative medicine

RC Rennert, M Sorkin, RK Garg… - Regenerative …, 2012 - Taylor & Francis
Tissue repair and regeneration are thought to involve resident cell proliferation as well as
the selective recruitment of circulating stem and progenitor cell populations through complex …

[HTML][HTML] Characterization of mesenchymal stem cells derived from rat bone marrow and adipose tissue: a comparative study

A Lotfy, M Salama, F Zahran, E Jones… - … journal of stem …, 2014 - synapse.koreamed.org
Methods and Results: For this comparison, immunophenotyping, the analysis of growth
rates, proliferation by colony forming unit-fibroblast assay, population doubling time, and …