Dynamic genome and transcriptional network‐based biomarkers and drugs: precision in breast cancer therapy

ID Kyrochristos, DE Ziogas… - Medicinal research …, 2019 - Wiley Online Library
Despite remarkable progress in medium‐term overall survival benefit in the adjuvant,
neoadjuvant and metastatic settings, with multiple recent targeted drug approvals, acquired …

Identification of lnc RNA s associated with early‐stage breast cancer and their prognostic implications

AK Deva Magendhra Rao, K Patel… - Molecular …, 2019 - Wiley Online Library
Breast cancer is the most common malignancy among women, with the highest incidence
rate worldwide. Dysregulation of long noncoding RNA s during the preliminary stages of …

lncRNA gene signatures for prediction of breast cancer intrinsic subtypes and prognosis

S Zhang, J Wang, T Ghoshal, D Wilkins, YY Mo… - Genes, 2018 - mdpi.com
Background: Breast cancer is intrinsically heterogeneous and is commonly classified into
four main subtypes associated with distinct biological features and clinical outcomes …

[HTML][HTML] A five-long non-coding RNA signature to improve prognosis prediction of clear cell renal cell carcinoma

D Shi, Q Qu, Q Chang, Y Wang, Y Gui, D Dong - Oncotarget, 2017 - ncbi.nlm.nih.gov
Recent works have reported that long non-coding RNAs (lncRNAs) play critical roles in
tumorigenesis and prognosis of cancers, suggesting the potential utility of lncRNAs as …

Long noncoding RNA H19 is a critical oncogenic driver and contributes to epithelial-mesenchymal transition in papillary thyroid carcinoma

WQ Liang, D Zeng, CF Chen, SM Sun… - Cancer Management …, 2019 - Taylor & Francis
Background Growing evidence has indicated that the long noncoding RNA H19 (lncRNA
H19), frequently deregulated in almost all tumor types tested, acted as a pivotal contributor …

Upregulated LncRNA‐CCAT1 promotes hepatocellular carcinoma progression by functioning as miR‐30c‐2‐3p sponge

J Zhang, M Cai, D Jiang, L Xu - Cell Biochemistry and Function, 2019 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the second leading cause of cancer‐related death over
the world. It is well studied that long noncoding RNA colon cancer–associated transcript‐1 …

DSCAM-AS1-driven proliferation of breast cancer cells involves regulation of alternative exon splicing and 3′-end usage

J Elhasnaoui, V Miano, G Ferrero, E Doria, AE Leon… - Cancers, 2020 - mdpi.com
DSCAM-AS1 is a cancer-related long noncoding RNA with higher expression levels in
Luminal A, B, and HER2-positive Breast Carcinoma (BC), where its expression is strongly …

[HTML][HTML] A long non-coding RNA signature to improve prognostic prediction in clear cell renal cell carcinoma

J Zhang, X Zhang, C Piao, J Bi, Z Zhang, Z Li… - Biomedicine & …, 2019 - Elsevier
Background Accumulating research reports have indicated that long non-coding RNAs
(lncRNAs) are abnormally expressed in many types of cancers. However, few lncRNA …

The transcriptome‐wide landscape of molecular subtype‐specific mRNA expression profiles in acute myeloid leukemia

T Mou, Y Pawitan, M Stahl, M Vesterlund… - American journal of …, 2021 - Wiley Online Library
Molecular classification of acute myeloid leukemia (AML) aids prognostic stratification and
clinical management. Our aim in this study is to identify transcriptome‐wide mRNAs that are …

A comprehensive landscape of imaging feature-associated RNA expression profiles in human breast tissue

T Mou, J Liang, TN Vu, M Tian, Y Gao - Sensors, 2023 - mdpi.com
The expression abundance of transcripts in nondiseased breast tissue varies among
individuals. The association study of genotypes and imaging phenotypes may help us to …