Low-risk triple-negative breast cancers: Clinico-pathological and molecular features
Triple-negative breast cancers (TNBC) comprise biologically and clinically heterogeneous
diseases characterized by the lack of hormone receptors (HR) and HER2 expression. This …
diseases characterized by the lack of hormone receptors (HR) and HER2 expression. This …
Breast cancer during pregnancy as a special type of early-onset breast cancer: analysis of the tumor immune microenvironment and risk profiles
Breast cancer during pregnancy (PrBC) is a rare tumor with only a little information on its
immune landscape. Here, we sought to characterize the cellular composition of the tumor …
immune landscape. Here, we sought to characterize the cellular composition of the tumor …
Characterization of the immune microenvironment in malignant pleural mesothelioma reveals prognostic subgroups of patients
Malignant pleural mesothelioma (MPM) is a rare tumor with an extremely poor prognosis. Its
pathogenesis is related to an immune response against asbestos fibers. The T-lymphocytes …
pathogenesis is related to an immune response against asbestos fibers. The T-lymphocytes …
Breast cancer with brain metastasis: molecular insights and clinical management
M Ivanova, FM Porta, F Giugliano, C Frascarelli… - Genes, 2023 - mdpi.com
Breast cancer is the most frequently diagnosed malignancy worldwide and the leading
cause of cancer-related death among women. Brain metastases are a primary contributor to …
cause of cancer-related death among women. Brain metastases are a primary contributor to …
PTEN expression as a complementary biomarker for mismatch repair testing in breast cancer
Mismatch repair (MMR) analysis in breast cancer may help to inform immunotherapy
decisions but it lacks breast-specific guidelines. Unlike in other neoplasms, MMR protein …
decisions but it lacks breast-specific guidelines. Unlike in other neoplasms, MMR protein …
Osteoclast-like stromal giant cells in breast cancer likely belong to the spectrum of immunosuppressive tumor-associated macrophages
Background: Breast cancer with osteoclast-like stromal giant cells (OSGC) is an exceedingly
rare morphological pattern of invasive breast carcinoma. The tumor immune …
rare morphological pattern of invasive breast carcinoma. The tumor immune …
Immune microenvironment dynamics in breast cancer during pregnancy: impact of gestational age on tumor-infiltrating lymphocytes and prognosis
Background Breast cancer during pregnancy (PrBC) is a rare condition known for its
aggressive clinical behavior. The presence of tumor-infiltrating lymphocytes (TILs) has been …
aggressive clinical behavior. The presence of tumor-infiltrating lymphocytes (TILs) has been …
Malignancies in patients with celiac disease: Diagnostic challenges and molecular advances
Celiac disease (CD) is a multiorgan autoimmune disorder of the chronic intestinal disease
group characterized by duodenal inflammation in genetically predisposed individuals …
group characterized by duodenal inflammation in genetically predisposed individuals …
Building up a high-throughput screening platform to assess the heterogeneity of HER2 gene amplification in breast cancers
Targeted therapies against the human epidermal growth factor receptor 2 (HER2) have
radically changed the outcome of patients with HER2-positive breast cancers. However, a …
radically changed the outcome of patients with HER2-positive breast cancers. However, a …
Understanding the biology of volumetric muscle loss for an individualized exercise rehabilitation approach in breast cancer patients
Muscle maintenance relies on a multidimensional biologic balance that is extremely delicate
in breast cancer patients, particularly those with advanced-stage disease. The biology that …
in breast cancer patients, particularly those with advanced-stage disease. The biology that …