Machine learning for survival analysis: A survey

P Wang, Y Li, CK Reddy - ACM Computing Surveys (CSUR), 2019 - dl.acm.org
Survival analysis is a subfield of statistics where the goal is to analyze and model data
where the outcome is the time until an event of interest occurs. One of the main challenges …

[HTML][HTML] Lung cancer: understanding its molecular pathology and the 2015 WHO classification

K Inamura - Frontiers in oncology, 2017 - frontiersin.org
Lung cancer is the leading cause of cancer-related death worldwide due to late diagnoses
and limited treatment interventions. Recently, comprehensive molecular profiles of lung …

Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy

T Davoli, H Uno, EC Wooten, SJ Elledge - Science, 2017 - science.org
INTRODUCTION Aneuploidy, also known as somatic copy number alterations (SCNAs), is
widespread in human cancers and has been proposed to drive tumorigenesis. The …

[HTML][HTML] Predicting non-small cell lung cancer prognosis by fully automated microscopic pathology image features

KH Yu, C Zhang, GJ Berry, RB Altman, C Ré… - Nature …, 2016 - nature.com
Lung cancer is the most prevalent cancer worldwide, and histopathological assessment is
indispensable for its diagnosis. However, human evaluation of pathology slides cannot …

[HTML][HTML] Lung cancers: molecular characterization, clonal heterogeneity and evolution, and cancer stem cells

U Testa, G Castelli, E Pelosi - Cancers, 2018 - mdpi.com
Lung cancer causes the largest number of cancer-related deaths in the world. Most (85%) of
lung cancers are classified as non-small-cell lung cancer (NSCLC) and small-cell lung …

[HTML][HTML] Comprehensive molecular profiling of lung adenocarcinoma

Cancer Genome Atlas Research Network - Nature, 2014 - ncbi.nlm.nih.gov
Adenocarcinoma of the lung is the leading cause of cancer death worldwide. Here we report
molecular profiling of 230 resected lung adenocarcinomas using messenger RNA …

Biomarker development in the precision medicine era: lung cancer as a case study

AJ Vargas, CC Harris - Nature reviews cancer, 2016 - nature.com
Precision medicine relies on validated biomarkers with which to better classify patients by
their probable disease risk, prognosis and/or response to treatment. Although …

Supervised, unsupervised, and semi-supervised feature selection: a review on gene selection

JC Ang, A Mirzal, H Haron… - IEEE/ACM transactions …, 2015 - ieeexplore.ieee.org
Recently, feature selection and dimensionality reduction have become fundamental tools for
many data mining tasks, especially for processing high-dimensional data such as gene …

Comprehensive molecular profiling of lung adenocarcinoma: The cancer genome atlas research network

E Collisson, J Campbell, A Brooks, A Berger, W Lee… - Nature, 2014 - espace.curtin.edu.au
Adenocarcinoma of the lung is the leading cause of cancer death worldwide. Here we report
molecular profiling of 230 resected lung adenocarcinomas using messenger RNA …

Development and validation of an individualized immune prognostic signature in early-stage nonsquamous non–small cell lung cancer

B Li, Y Cui, M Diehn, R Li - JAMA oncology, 2017 - jamanetwork.com
Importance The prevalence of early-stage non–small cell lung cancer (NSCLC) is expected
to increase with recent implementation of annual screening programs. Reliable prognostic …