microRNA-based biomarkers in Alzheimer's disease (AD)
Y Zhao, V Jaber, PN Alexandrov, A Vergallo… - Frontiers in …, 2020 - frontiersin.org
Alzheimer's disease (AD) is a multifactorial, age-related neurological disease characterized
by complex pathophysiological dynamics taking place at multiple biological levels, including …
by complex pathophysiological dynamics taking place at multiple biological levels, including …
Loss of TDP-43 splicing repression occurs early in the aging population and is associated with Alzheimer's disease neuropathologic changes and cognitive decline
LATE-NC, the neuropathologic changes of limbic-predominant age-related TAR DNA-
binding protein 43 kDa (TDP-43) encephalopathy are frequently associated with Alzheimer's …
binding protein 43 kDa (TDP-43) encephalopathy are frequently associated with Alzheimer's …
[HTML][HTML] Age-related hearing loss associated with differences in the neural correlates of feature binding in visual working memory
The underlying neural mechanisms underpinning the association between age-related
hearing loss (ARHL) and dementia remain unclear. A limitation has been the lack of …
hearing loss (ARHL) and dementia remain unclear. A limitation has been the lack of …
Disease modelling of cognitive outcomes and biomarkers in the European Prevention of Alzheimer's Dementia Longitudinal Cohort
A key challenge for the secondary prevention of Alzheimer's dementia is the need to identify
individuals early on in the disease process through sensitive cognitive tests and biomarkers …
individuals early on in the disease process through sensitive cognitive tests and biomarkers …
Accelerated decline in white matter microstructure in subsequently impaired older adults and its relationship with cognitive decline
AT Shafer, OA Williams, E Perez, Y An… - Brain …, 2022 - academic.oup.com
Little is known about a longitudinal decline in white matter microstructure and its
associations with cognition in preclinical dementia. Longitudinal diffusion tensor imaging …
associations with cognition in preclinical dementia. Longitudinal diffusion tensor imaging …
Qualitative verbal fluency components as prognostic factors for developing Alzheimer's dementia and mild cognitive impairment: results from the population-based …
Background and Objectives: The aim of the present study was to investigate the prognostic
value of the qualitative components of verbal fluency (clustering, switching, intrusions, and …
value of the qualitative components of verbal fluency (clustering, switching, intrusions, and …
Sensory impairment and algorithmic classification of early cognitive impairment
INTRODUCTION Sensory impairment (SI) is linked to cognitive decline, but its association
with early cognitive impairment (ECI) is unclear. METHODS Sensory functions (vision …
with early cognitive impairment (ECI) is unclear. METHODS Sensory functions (vision …
Modifiable lifestyle activities affect cognition in cognitively healthy middle-aged individuals at risk for late-life Alzheimer's Disease
A Heneghan, F Deng, K Wells, K Ritchie… - Journal of …, 2023 - content.iospress.com
Background: It is now acknowledged that Alzheimer's disease (AD) processes are present
decades before the onset of clinical symptoms, but it remains unknown whether lifestyle …
decades before the onset of clinical symptoms, but it remains unknown whether lifestyle …
Cross-sectional association between blood cell phenotypes, cognitive function, and brain imaging measures in the community-based Framingham heart study
Background: Peripheral inflammation is associated with increased risk for dementia.
Neutrophil to lymphocyte ratio (NLR), red cell distribution width (RDW), and mean platelet …
Neutrophil to lymphocyte ratio (NLR), red cell distribution width (RDW), and mean platelet …
Longitudinal trajectory effects of different MCI subtypes on general cognitive and daily functions in a population-based cohort of older adults
M Yuan, X Long, Z Zhang, M Rong, S Lian… - Journal of Psychiatric …, 2024 - Elsevier
Objectives To identify different mild cognitive impairment (MCI) phenotypes based on
substantial relative impairment in specific cognitive domains and then characterize the …
substantial relative impairment in specific cognitive domains and then characterize the …