Trends in insulin resistance: insights into mechanisms and therapeutic strategy

M Li, X Chi, Y Wang, S Setrerrahmane… - Signal transduction and …, 2022 - nature.com
The centenary of insulin discovery represents an important opportunity to transform diabetes
from a fatal diagnosis into a medically manageable chronic condition. Insulin is a key …

[HTML][HTML] Gut microbes in metabolic disturbances. Promising role for therapeutic manipulations?

P Portincasa, M Khalil, A Graziani, G Frühbeck… - European Journal of …, 2024 - Elsevier
The prevalence of overweight, obesity, type 2 diabetes, metabolic syndrome and steatotic
liver disease is rapidly increasing worldwide with a huge economic burden in terms of …

Gut microbiome and its impact on obesity and obesity-related disorders

S Sankararaman, K Noriega, S Velayuthan… - Current …, 2023 - Springer
Abstract Purpose of Review The prevalence of overweight and obesity has been increasing
worldwide at an alarming rate. Gut microbiota intimately influence host energy metabolism …

A predictive regression model of the obesity-related inflammatory status based on gut microbiota composition

P Aranaz, O Ramos-Lopez, A Cuevas-Sierra… - International Journal of …, 2021 - nature.com
Background and aim Fecal microbiome disturbances are linked to different human diseases.
In the case of obesity, gut microbiota seems to play a role in the development of low-grade …

Elucidation of the interaction effect between dietary fiber and bound polyphenol components on the anti-hyperglycemic activity of tea residue dietary fiber

H Huang, J Chen, X Hu, Y Chen, J Xie, T Ao… - Food & Function, 2022 - pubs.rsc.org
Dietary fiber intake is beneficial for the prevention of some chronic metabolic diseases.
Considering the characteristic that dietary fiber from tea residues (TRDF) is rich in bound …

Gut microbiota and obesity: New insights

Y Sarmiento-Andrade, R Suárez, B Quintero… - Frontiers in …, 2022 - frontiersin.org
Obesity is a pathology whose incidence is increasing throughout the world. There are many
pathologies associated with obesity. In recent years, the influence of the microbiota on both …

Mulberry (Morus alba L.) leaf polysaccharide ameliorates insulin resistance‐ and adipose deposition‐associated gut microbiota and lipid metabolites in high‐fat diet …

X Zhao, Z Fu, M Yao, Y Cao, T Zhu… - Food Science & …, 2022 - Wiley Online Library
Dietary supplements are currently being used to ameliorate metabolic alterations via
maintaining gut microflora balance. Mulberry leaf is known as medicine homologous food for …

Dietary fiber for the prevention of childhood obesity: a focus on the involvement of the gut microbiota

Z Yang, M Yang, EC Deehan, C Cai, KL Madsen… - Gut …, 2024 - Taylor & Francis
Given the worldwide epidemic of overweight and obesity among children, evidence-based
dietary recommendations are fundamentally important for obesity prevention. Although the …

Recent insights of obesity-induced gut and adipose tissue dysbiosis in type 2 diabetes

D Patra, D Banerjee, P Ramprasad, S Roy… - Frontiers in Molecular …, 2023 - frontiersin.org
An imbalance in microbial homeostasis, referred to as dysbiosis, is critically associated with
the progression of obesity-induced metabolic disorders including type 2 diabetes (T2D) …

Prevalence of prediabetes in children and adolescents by class of obesity

S Pedicelli, D Fintini, L Ravà, E Inzaghi… - Pediatric …, 2022 - Wiley Online Library
Background To evaluate prevalence of prediabetes (impaired fasting glucose, IFG; impaired
glucose tolerance, IGT; and high glycated haemoglobin, h‐HbA1c) in children and …