The SARS-CoV-2 virus spreading across the world has led to surges of COVID-19 illness,
hospitalizations, and death. The complex and multifaceted pathophysiology of life …

Aims: To evaluate the efficacy and safety of hydroxychloroquine/chloroquine, with or without
azithromycin, in treating hospitalized COVID-19 patients. Materials & methods: Data from …

Objectives Severe systemic inflammation associated with some stages of COVID-19 and in
fatal cases led therapeutic agents developed or used frequently in Rheumatology being at …

Objective To summarise the available information on efficacy and safety of
immunomodulatory agents in SARS-CoV-2 infection. Methods As part of a European …

Despite the global effort to mitigate the spread, coronavirus disease 2019 (COVID-19) has
become a pandemic that took more than 2 million lives. There are numerous ongoing …

Introduction: To explore the incidence of pro-arrhythmic effects such as corrected QT interval
(QTc) prolongation, arrhythmic events and myocardial injury of azithromycin as administered …

Introduction: Post-marketing identification and report of unknown adverse drug reactions
(ADRs) are crucial for patient safety. However, complete information on unknown ADRs …

Objective To evaluate the association of a prolonged corrected QT (QTc) interval in severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and its association with in …

The emergency of the coronavirus disease 2019 (COVID-19) pandemic led to the off-label
use of drugs without data on their toxicity profiles in patients with COVID-19, or on their …

Background At onset of coronavirus disease 2019 (COVID-19) pandemic,
hydroxychloroquine (HCQ) was repurposed for treatment of patients based on reports that it …