Background A significant proportion of patients with chronic kidney disease and secondary
hyperparathyroidism (HPT) remain hyperparathyroid after kidney transplantation, a state …

Uremic secondary hyperparathyroidism is a multifactorial and complex disease often
present in advanced stages of chronic kidney disease. The accumulation of phosphate, the …

Background Kidney transplantation corrects or improves many complications of chronic
kidney disease, but its impact on disordered mineral metabolism is incompletely understood …

The risk of mineral and bone disorders among patients with chronic kidney disease is
substantially elevated, owing largely to alterations in calcium, phosphorus, vitamin D …

Background Renal transplant allograft function in patients with tertiary hyperparathyroidism
who are treated with cinacalcet versus parathyroidectomy remains unclear. Methods This is …

The calcium-sensing receptor (CaSR) plays a pivotal role in regulating systemic Ca 2+
homeostasis and is a target for drugs designed to treat certain disorders of bone and mineral …

Background Hyperparathyroidism is common in patients with chronic kidney disease with
reduced renal function and has been observed after kidney transplantation. The optimal …

After successful kidney transplantation, accumulated waste products and electrolytes are
excreted and regulatory hormones return to normal levels. Despite the improvement in …

Introduction Tertiary hyperparathyroidism (tHPT), ie, persistent HPT after kidney
transplantation, affects 17–50% of transplant recipients. Treatment of tHPT is mandatory …

Background Persistent hyperparathyroidism (HPT) after renal transplantation (RTx), termed
tertiary HPT (THPT), is not uncommon. However, risk factors and appropriate operative …