Alzheimer's disease (AD) is the most common age-related neurodegenerative disorder that
is characterized by amyloid β-protein deposition in senile plaques, neurofibrillary tangles …

Alzheimer's disease (AD) is the most common type of dementia and is characterized by the
accumulation of amyloid (Aβ) plaques and neurofibrillary tangles in the brain. Much attention …

The endoplasmic reticulum (ER) as an intracellular Ca2+ store not only sets up cytosolic
Ca2+ signals, but, among other functions, also assembles and folds newly synthesized …

Alzheimer's disease (AD) is a progressive neurodegenerative disease involving aggregation
of misfolded proteins inside the neuron causing prolonged cellular stress. The …

The endoplasmic reticulum (ER) is the site of synthesis and folding of membrane and
secretory proteins, which, collectively, represent a large fraction of the total protein output of …

The common underlying feature of most neurodegenerative diseases such as Alzheimer
disease (AD), prion diseases, Parkinson disease (PD), and amyotrophic lateral sclerosis …

Introduction• ER stress and the UPR‐The IRE1 axis: non‐conventional splicing of XBP1
mRNA‐The PERK axis: attenuation of translation‐The ATF6 axis: regulated proteolytic …

Oxidative stress and endoplasmic reticulum (ER) stress have been associated with
Alzheimer's disease (AD) progression. In this study we analyzed whether oxidative stress …

Clusterin, also known as apolipoprotein J, is a versatile chaperone molecule which contains
several amphipathic and coiled-coil α-helices, typical characteristics of small heat shock …

Alzheimer's Disease (AD) is a neurodegenerative disorder characterized by progressive
neuronal loss. AD is associated with aberrant processing of the amyloid precursor protein …