Toll-like receptors (TLRs) are essential receptors involved in inflammation and innate
immunity. Various types of cancer cells, as well as innate immune cells, express TLRs …

The aberrant glycosylation is a hallmark of cancer progression and chemoresistance. It is
also an immune therapeutic target for various cancers. Tunicamycin (TM) is one of the potent …

Breast cancer (BC) represents the most prevalent cancer in women at any age after puberty.
From a pathogenetic prospective, despite a wide array of risk factors being identified thus …

In 2020, there were 377,713 new oral and lip cancer diagnoses and 177,757 deaths. Oral
cancer is a malignancy of the head and neck region, and 90% of cases are squamous cell …

Protein-protein interactions (PPIs) form complex cellular networks fundamental to many key
biological processes, including signal transduction, cell proliferation and DNA repair. In …

The cancer cells that are not normal can grow into tumors, invade surrounding tissues, and
travel to other parts of the body via the lymphatic or circulatory systems. Interleukins, a vital …

Interleukin-33 (IL-33) is a cytokine belonging to the IL-1 family. It is primarily associated with
type 2 immune responses. It interacts with a receptor complex on immune cells in reaction to …

Advances in pediatric cancer treatment over the past three decades have focused on the
intensification of conventional chemotherapy. While this approach was successful, we have …

Immunotherapy has revolutionized the field of cancer treatment, changing the standard of
care to the use of immune checkpoint inhibitors. Radiotherapy can boost anti-tumour …

We propose a mathematical kinetic framework to investigate interactions between tumor
cells and the immune system, focusing on the spatial dynamics of tumor progression and …