[HTML][HTML] The emerging role of the gut microbiota and its application in inflammatory bowel disease

X Wang, J Peng, P Cai, Y Xia, C Yi, A Shang… - Biomedicine & …, 2024 - Elsevier
Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is a
complex disorder with an unknown cause. However, the dysbiosis of the gut microbiome has …

Potential roles of gut microbes in biotransformation of natural products: An overview

Y Zhao, X Zhong, J Yan, C Sun, X Zhao… - Frontiers in …, 2022 - frontiersin.org
Natural products have been extensively applied in clinical practice, characterized by multi-
component and multi-target, many pharmacodynamic substances, complex action …

[HTML][HTML] Microbiota of the gastrointestinal tract: Friend or foe?

MA Senchukova - World Journal of Gastroenterology, 2023 - ncbi.nlm.nih.gov
The gut microbiota is currently considered an external organ of the human body that
provides important mechanisms of metabolic regulation and protection. The gut microbiota …

Gut microbiota: a new avenue to reveal pathological mechanisms of constipation

L Yang, Y Wang, Y Zhang, W Li, S Jiang, D Qian… - Applied Microbiology …, 2022 - Springer
Constipation is very pervasive all over the world. It is a common multifactorial
gastrointestinal disease, and its etiology and pathomechanism are not completely clear …

[HTML][HTML] Understanding vaginal biofilms: The first step in harnessing antimicrobial nanomedicine

S Obuobi, N Škalko-Basnet - Journal of Controlled Release, 2024 - Elsevier
In spite of multipurpose technologies offering broad-spectrum prevention for sexually
transmitted infections (STIs) and contraception, the STIs incidences rise worldwide. The …

Interactions between toll‐like receptors signaling pathway and gut microbiota in host homeostasis

L Chen, L Zhang, H Hua, L Liu, Y Mao… - Immunity, Inflammation …, 2024 - Wiley Online Library
Abstract Background Toll‐like receptors (TLRs) are a family of fundamental pattern
recognition receptors in the innate immune system, constituting the first line of defense …

Sleep deprivation impairs intestinal mucosal barrier by activating endoplasmic reticulum stress in goblet cells

G Li, M Gao, S Zhang, T Dai, F Wang, J Geng… - The American Journal of …, 2024 - Elsevier
Sleep deficiency is associated with intestinal inflammatory conditions and is increasingly
recognized as a public health concern worldwide. However, the effects of sleep deficiency …

Yeast oral vaccines against infectious diseases

N Austriaco - Frontiers in Microbiology, 2023 - frontiersin.org
Vaccines that are delivered orally have several advantages over their counterparts that are
administered via injection. Despite the advantages of oral delivery, however, approved oral …

Tuft cells utilize taste signaling molecules to respond to the pathobiont microbe Ruminococcus gnavus in the proximal colon

H Lei, D Yu, YB Xue, YH Li, SM Gong… - Frontiers in …, 2023 - frontiersin.org
Tuft cells are a type of rare epithelial cells that have been recently found to utilize taste
signal transduction pathways to detect and respond to various noxious stimuli and …

Cultivating complexity: Advancements in establishing in vitro models for the mucus‐adhering gut microbiota

M Calvigioni, D Mazzantini, F Celandroni… - Microbial …, 2024 - Wiley Online Library
A healthy mucus is essential for maintaining intestinal homeostasis and overall well‐being.
In recent years, extensive research focused on understanding the intricate interactions …