Alternative therapeutics to control antimicrobial resistance: a general perspective
Antimicrobial Resistance (AMR) is a critical global health challenge, and in this review
article, we examine the limitations of traditional therapeutic methods and the emerging role …
article, we examine the limitations of traditional therapeutic methods and the emerging role …
Key challenges in TB drug discovery: A perspective
BB Shaik, R Karpoormath - Bioorganic & Medicinal Chemistry Letters, 2024 - Elsevier
Over the past 2000 years, tuberculosis (TB) has been responsible for more deaths than any
other infectious disease. In recent years, there has been a recovery of research and …
other infectious disease. In recent years, there has been a recovery of research and …
Ajoene: a natural compound with enhanced antimycobacterial and antibiofilm properties mediated by efflux pump modulation and ROS generation against M …
Tuberculosis (TB) continues to be a primary worldwide health concern due to relatively
ineffective treatments. The prolonged duration of conventional antibiotic therapy warrants …
ineffective treatments. The prolonged duration of conventional antibiotic therapy warrants …
Discovery of acetohydroxyacid synthase inhibitors as anti-tuberculosis lead compounds from natural products
Y Niu, Z Wu, Q Hu, Y Wu, Q Jiang, X Yang - Bioorganic & Medicinal …, 2025 - Elsevier
Acetohydroxy acid synthase (AHAS) is a key enzyme that catalyzes the synthesis of
branched-chain amino acids, which is indispensable for the survival and growth of …
branched-chain amino acids, which is indispensable for the survival and growth of …
Antimicrobial Resistance and Factors: An Introduction
V Soni, AB Doltrario, EH Rosenn, S Das… - … Resistance: Factors to …, 2024 - Springer
Antimicrobial resistance (AMR) stands as a parallel pandemic, growing at an astonishing
rate. Given the failing efficacy of traditional therapeutic approaches, it becomes imperative to …
rate. Given the failing efficacy of traditional therapeutic approaches, it becomes imperative to …
Antibiotic Resistance in Mycobacterium Tuberculosis and Non-Tuberculous Mycobacteria
R Wamalwa, B Guyah, N Shaviya - African Journal of Empirical Research, 2024 - ajol.info
Mycobacterium tuberculosis (MTB) and non-tuberculous mycobacteria (NTM) antibiotic
resistance presents an important challenge to the treatment of mycobacterial infections. The …
resistance presents an important challenge to the treatment of mycobacterial infections. The …