Gastric cancer remains one of the most common cancers worldwide and one of the leading
cause for cancer-related deaths. Gastric adenocarcinoma is a multifactorial disease that is …

In Mediterranean cuisine and culture, olive oil and olive fruits play a significant role. Many
people believe that those who consume olive oil and its fruit live longer and have a …

CRISPR/Cas9 has emerged as a powerful new tool to systematically probe gene function.
We compared the performance of CRISPR to RNAi-based loss-of-function screens for the …

Atherosclerosis is a disease of chronic inflammation. We investigated the roles of the
cytokines IL-4 and IL-13, the classical activators of STAT6, in the resolution of …

Chemotherapy is essential to most patients with gastric cancer and the anticancer drug,
irinotecan (CPT-11), and its metabolite, SN-38, an inhibitor of DNA topoisomerase I, are first …

Prostaglandins exert a profound influence over the adhesive, migratory, and invasive
behavior of cells during the development and progression of cancer. Cyclooxygenase‐2 …

The importance of Wnt/β-catenin signaling in cancer stem cells (CSCs) has been
acknowledged; however, the mechanism through which it regulates the biological function of …

The Wnt/β-catenin signaling pathway plays crucial roles in embryonic development and the
development of multiple types of cancer, and its aberrant activation provides cancer cells …

Familial adenomatous polyposis (FAP) is a hereditary colorectal cancer syndrome
characterized by colorectal adenomas and a near 100% lifetime risk of colorectal cancer …

Background Deregulated inflammatory responses are known to play a pivotal role in cancer
initiation and progression. Tumor microenvironment is associated with the presence of a …