Nutrition rich in carotenoids is well known to prevent cell damage, premature skin aging, and
skin cancer. Cutaneous carotenoids can be enriched in the skin by nutrition and topically …

In the outermost layer of the skin, the stratum corneum (SC), ceramides form a diverse and
essential pool of lipids. Due to their diversity and the limited availability of synthetic …

Natural ceramide, a biologically active compound present in plants, has been used widely in
food, cosmetics, and pharmaceutical industries. Abundant ceramide has been detected in …

Atopic dermatitis (AD) is the most common inflammatory skin disease in children. In the
study, ultra high performance liquid chromatography–mass spectrometry was used to …

The stratum corneum (SC) provides the main barrier properties in native skin. The barrier
function is attributed to the intercellular lipids, forming continuous multilamellar membranes …

The penetration of small molecules through the human skin is a major issue for both safety
and efficacy issues in cosmetics and pharmaceutic domains. To date, the quantification of …

Understanding the penetration mechanisms of drugs into human skin is a key issue in
pharmaceutical and cosmetics research. To date, the techniques available for percutaneous …

Several skin diseases such as psoriasis and atopic dermatitis are associated with the
depletion or disturbance of stratum corneum (SC) lipids such as ceramides (CERs), free fatty …

The outermost layer of the mammalian skin, the stratum corneum (SC), is a very thin
structure and realizes simultaneously the main barrier properties. The penetration barrier for …

The stratum corneum, the outermost layer of the epidermis, is the most important skin barrier
against exogenous physical and chemical effects, in addition to protecting against …