J Zhao, D Peter, I Brandina, X Liu, WP Galej - Molecular Cell, 2025 - cell.com
The minor spliceosome catalyzes excision of U12-dependent introns from precursors of eukaryotic messenger RNAs (pre-mRNAs). This process is critical for many cellular …
Minor spliceosome is responsible for recognizing and excising a specific subset of divergent introns during the pre-mRNA splicing process. Mutations in the unique snRNA and protein …
Despite the fact that 0.5% of human introns are processed by the U11/U12 minor spliceosome, the latter influences gene expression across multiple cellular processes. The …
The presence of autoantibodies is a serological hallmark of SSc, as it has been reported that 95% of patients present anti-nuclear autoantibodies (ANAs) by indirect immunofluorescence …