Aerosol pulmonary immune engineering

ER Sudduth, M Trautmann-Rodriguez, N Gill… - Advanced Drug Delivery …, 2023 - Elsevier
Aerosolization of immunotherapies poses incredible potential for manipulating the local
mucosal-specific microenvironment, engaging specialized pulmonary cellular defenders …

The potential use of mesenchymal stem cells and their derived exosomes as immunomodulatory agents for COVID‐19 patients

FA Alzahrani, IM Saadeldin, A Ahmad… - Stem cells …, 2020 - Wiley Online Library
A novel severe acute respiratory syndrome coronavirus (SARS‐CoV‐2) causing lethal acute
respiratory disease emerged in December 2019. The World Health Organization named this …

[HTML][HTML] Can stem cells beat COVID-19: advancing stem cells and extracellular vesicles toward mainstream medicine for lung injuries associated with SARS-CoV-2 …

W Chrzanowski, SY Kim, L McClements - Frontiers in Bioengineering …, 2020 - frontiersin.org
A number of medicines are currently under investigation for the treatment of COVID-19
disease including anti-viral, anti-malarial and anti-inflammatory agents. While these …

State of the art review of cell therapy in the treatment of lung disease, and the potential for aerosol delivery

H Brave, R MacLoughlin - International Journal of Molecular Sciences, 2020 - mdpi.com
Respiratory and pulmonary diseases are among the leading causes of death globally.
Despite tremendous advancements, there are no effective pharmacological therapies …

ACE2 Receptor‐Targeted Inhaled Nanoemulsions Inhibit SARS‐CoV‐2 and Attenuate Inflammatory Responses

H Wang, S Luo, M Xie, Z Chen, Y Zhang… - Advanced …, 2024 - Wiley Online Library
Three kinds of coronaviruses are highly pathogenic to humans, and two of them mainly
infect humans through Angiotensin‐converting enzyme 2 (ACE2) receptors. Therefore …

Effervescent atomizer as novel cell spray technology to decrease the gas-to-liquid ratio

AL Thiebes, S Klein, J Zingsheim, GH Möller, S Gürzing… - Pharmaceutics, 2022 - mdpi.com
Cell spraying has become a feasible application method for cell therapy and tissue
engineering approaches. Different devices have been used with varying success. Often, twin …

Predicting the composition and size distribution of dry particles for aerosols and sprays of suspension: A Monte Carlo approach

MYT Chow, PCL Kwok, R Yang, HK Chan - International Journal of …, 2020 - Elsevier
A volume-based Monte Carlo simulation describing the distribution of polydisperse particles
aerosolized in polydisperse droplets was developed. The algorithm addressed some major …

Aerosol‐based airway epithelial cell delivery improves airway regeneration and repair

E Kardia, ES Ch'ng, BH Yahaya - Journal of Tissue …, 2018 - Wiley Online Library
Aerosol‐based cell therapy has emerged as a novel and promising therapeutic strategy for
treating lung diseases. The goal of this study was to determine the safety and efficacy of …

Stimulatory secretions of airway epithelial cells accelerate early repair of tracheal epithelium

E Kardia, R Mohamed, BH Yahaya - Scientific Reports, 2017 - nature.com
Airway stem/progenitor epithelial cells (AECs) are notable for their differentiation capacities
in response to lung injury. Our previous finding highlighted the regenerative capacity of …

吸入骨髓间充质干细胞来源外泌体减轻慢性阻塞性肺疾病的炎性损伤

王敏, 尹秀山, 王盈熹, 张妍, 赵龙, 夏书月 - 中国组织工程研究, 2023 - cjter.com
吸入骨髓间充质干细胞来源外泌体减轻慢性阻塞性肺疾病的炎性损伤 Page 1 Chinese Journal
of Tissue Engineering Research|Vol 27|No.6|February 2023|827 中国组织工程研究 Chinese …