Gastrointestinal (GI) cancers, as the most common human malignancies are always
considered one of the most important health challenges in the world. Late diagnosis in …

Abstract Background Squamous cell carcinoma (SqCC) is a subtype of non-small cell lung
cancer for which patient prognosis remains poor. The extracellular matrix (ECM) is critical in …

The effective treatment of advanced cervical cancer remains challenging. Herein, single‐
nucleus RNA sequencing (snRNA‐seq) and SpaTial enhanced resolution omics …

Activating invasion and metastasis are one of the primary hallmarks of cancer, the latter
representing the leading cause of death in cancer patients. Whilst many advances in this …

Given the key roles of cancer associated fibroblasts (CAFs) in shaping tumor stroma, this
study shows a CAF-associated ITGB1-inactivating peptide-enriched membrane …

Inflammatory cancer-associated fibroblasts (iCAFs) are closely related to progression,
anticancer therapeutic resistance, and poor prognosis of bladder cancer (BCa). However …

Abstract Background Circular RNAs (circRNAs) have been reported to be important
regulators of the development and progression of various carcinomas. However, the role of …

Tumors, unlike normal tissue, have vascular anomalies and create interstitial flow (IF), which
allows soluble substances from cancer cells to be transported directionally toward the tumor …

The tumor microenvironment (TM), consisting of the extracellular matrix (ECM), fibroblasts,
endothelial cells, and immune cells, might affect tumor invasiveness and the outcome of …

Simple Summary An analysis of the presence of mutations of 105 genes in appendiceal
cancers through the lens of the reviewed literature supports the view that in most of them, the …