Mass spectrometry-based techniques to elucidate the sugar code

M Grabarics, M Lettow, C Kirschbaum, K Greis… - Chemical …, 2021 - ACS Publications
Cells encode information in the sequence of biopolymers, such as nucleic acids, proteins,
and glycans. Although glycans are essential to all living organisms, surprisingly little is …

Spatial metabolomics and imaging mass spectrometry in the age of artificial intelligence

T Alexandrov - Annual review of biomedical data science, 2020 - annualreviews.org
Spatial metabolomics is an emerging field of omics research that has enabled localizing
metabolites, lipids, and drugs in tissue sections, a feat considered impossible just two …

Ion mobility collision cross-section atlas for known and unknown metabolite annotation in untargeted metabolomics

Z Zhou, M Luo, X Chen, Y Yin, X Xiong, R Wang… - Nature …, 2020 - nature.com
The metabolome includes not just known but also unknown metabolites; however,
metabolite annotation remains the bottleneck in untargeted metabolomics. Ion mobility …

Plants metabolome study: Emerging tools and techniques

MK Patel, S Pandey, M Kumar, MI Haque, S Pal… - Plants, 2021 - mdpi.com
Metabolomics is now considered a wide-ranging, sensitive and practical approach to
acquire useful information on the composition of a metabolite pool present in any organism …

[HTML][HTML] Emerging applications of metabolomics in food science and future trends

W Wu, L Zhang, X Zheng, Q Huang, MA Farag, R Zhu… - Food Chemistry: X, 2022 - Elsevier
Metabolomics is a relatively new component in systems biology that focuses on the high-
throughput characterization of small molecular metabolites in biological systems. It is widely …

PeakDecoder enables machine learning-based metabolite annotation and accurate profiling in multidimensional mass spectrometry measurements

A Bilbao, N Munoz, J Kim, DJ Orton, Y Gao… - Nature …, 2023 - nature.com
Multidimensional measurements using state-of-the-art separations and mass spectrometry
provide advantages in untargeted metabolomics analyses for studying biological and …

Nanospray desorption electrospray ionization (Nano-DESI) mass spectrometry imaging with high ion mobility resolution

LX Jiang, E Hernly, H Hu, RT Hilger… - Journal of the …, 2023 - ACS Publications
Untargeted separation of isomeric and isobaric species in mass spectrometry imaging (MSI)
is challenging. The combination of ion mobility spectrometry (IMS) with MSI has emerged as …

Moisture modulates soil reservoirs of active DNA and RNA viruses

R Wu, MR Davison, Y Gao, CD Nicora… - Communications …, 2021 - nature.com
Soil is known to harbor viruses, but the majority are uncharacterized and their responses to
environmental changes are unknown. Here, we used a multi-omics approach …

Recent advances in proteomics and metabolomics in plants

S Yan, R Bhawal, Z Yin, TW Thannhauser… - Molecular Horticulture, 2022 - Springer
Over the past decade, systems biology and plant-omics have increasingly become the main
stream in plant biology research. New developments in mass spectrometry and …

Highly accurate and large-scale collision cross sections prediction with graph neural networks

R Guo, Y Zhang, Y Liao, Q Yang, T Xie, X Fan… - Communications …, 2023 - nature.com
The collision cross section (CCS) values derived from ion mobility spectrometry can be used
to improve the accuracy of compound identification. Here, we have developed the Structure …