[HTML][HTML] LncRNA ADAMTS9-AS2 inhibits gastric cancer (GC) development and sensitizes chemoresistant GC cells to cisplatin by regulating miR-223-3p/NLRP3 axis
N Ren, T Jiang, C Wang, S Xie, Y Xing, D Piao… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
The role of LncRNA ADAMTS9-AS2 in the regulation of chemoresistance of gastric cancer
(GC) is largely unknown. Here we found that LncRNA ADAMTS9-AS2 was low-expressed in …
(GC) is largely unknown. Here we found that LncRNA ADAMTS9-AS2 was low-expressed in …
[PDF][PDF] Evolutionary perspective on mammalian inorganic polyphosphate (polyP) biology
Inorganic polyphosphate (polyP), the polymeric form of phosphate, is attracting ever-growing
attention due to the many functions it appears to perform within mammalian cells. This essay …
attention due to the many functions it appears to perform within mammalian cells. This essay …
Inorganic polyphosphate—regulator of cellular metabolism in homeostasis and disease
Inorganic polyphosphate (polyP), a simple anionic polymer consisting of even hundreds of
orthophosphate units, is a universal molecule present in both simple and complex …
orthophosphate units, is a universal molecule present in both simple and complex …
Modification of histidine repeat proteins by inorganic polyphosphate
N Neville, K Lehotsky, Z Yang, KA Klupt, A Denoncourt… - Cell Reports, 2023 - cell.com
Inorganic polyphosphate (polyP) is a linear polymer of orthophosphate that is present in
nearly all organisms studied to date. A remarkable function of polyP involves its attachment …
nearly all organisms studied to date. A remarkable function of polyP involves its attachment …
Polyphosphate drives bacterial heterochromatin formation
Heterochromatin is most often associated with eukaryotic organisms. Yet, bacteria also
contain areas with densely protein-occupied chromatin that appear to silence gene …
contain areas with densely protein-occupied chromatin that appear to silence gene …
Polyphosphate degradation by Nudt3-Zn2+ mediates oxidative stress response
B Samper-Martín, A Sarrias, B Lázaro… - Cell Reports, 2021 - cell.com
Polyphosphate (polyP) is a polymer of hundreds of phosphate residues present in all
organisms. In mammals, polyP is involved in crucial physiological processes, including …
organisms. In mammals, polyP is involved in crucial physiological processes, including …
Polyphosphate Functions In Vivo as an Iron Chelator and Fenton Reaction Inhibitor
Maintaining cellular iron homeostasis is critical for organismal survival. Whereas iron
depletion negatively affects the many metabolic pathways that depend on the activity of iron …
depletion negatively affects the many metabolic pathways that depend on the activity of iron …
[HTML][HTML] A broad response to intracellular long-chain polyphosphate in human cells
E Bondy-Chorney, I Abramchuk, R Nasser, C Holinier… - Cell Reports, 2020 - cell.com
Polyphosphates (polyPs) are long chains of inorganic phosphates linked by
phosphoanhydride bonds. They are found in all kingdoms of life, playing roles in cell growth …
phosphoanhydride bonds. They are found in all kingdoms of life, playing roles in cell growth …
A mammalian model reveals inorganic polyphosphate channeling into the nucleolus and induction of a hyper-condensate state
Inorganic polyphosphate (polyP) is a ubiquitous polymer that controls fundamental
processes. To overcome the absence of a genetically tractable mammalian model, we …
processes. To overcome the absence of a genetically tractable mammalian model, we …
Reentrant DNA shells tune polyphosphate condensate size
The inorganic biopolymer polyphosphate (polyP) occurs in all domains of life and affects
myriad cellular processes. A longstanding observation is polyP's frequent proximity to …
myriad cellular processes. A longstanding observation is polyP's frequent proximity to …