Chronic wounds

V Falanga, RR Isseroff, AM Soulika… - Nature Reviews …, 2022 - nature.com
Chronic wounds are characterized by their inability to heal within an expected time frame
and have emerged as an increasingly important clinical problem over the past several …

Diabetes in sub-Saharan Africa: from clinical care to health policy

R Atun, JI Davies, EAM Gale… - The lancet Diabetes & …, 2017 - thelancet.com
Executive summary Rapid demographic, sociocultural, and economic transitions are driving
increases in the risk and prevalence of diabetes and other non-communicable diseases …

The current burden of diabetic foot disease

M Edmonds, C Manu, P Vas - Journal of clinical orthopaedics and trauma, 2021 - Elsevier
Neuropathy and ischaemia are two great pathologies of the diabetic foot which lead to the
characteristic features of foot ulceration (neuropathic and ischaemic) and Charcot …

Association of diabetic foot ulcer and death in a population‐based cohort from the United Kingdom

JW Walsh, OJ Hoffstad, MO Sullivan… - Diabetic …, 2016 - Wiley Online Library
Aims The presence of diabetic foot ulcers is strongly associated with an increased risk of
death. In this study, we investigate whether the effects of diabetes‐associated complications …

Diabetic neuropathy: clinical manifestations and current treatments

BC Callaghan, HT Cheng, CL Stables… - The lancet …, 2012 - thelancet.com
Diabetic peripheral neuropathy is a prevalent, disabling disorder. The most common
manifestation is distal symmetrical polyneuropathy (DSP), but many patterns of nerve injury …

Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus

Z Liu, JC Dumville, RJ Hinchliffe… - Cochrane Database …, 2018 - cochranelibrary.com
Background Foot wounds in people with diabetes mellitus (DM) are a common and serious
global health issue. People with DM are prone to developing foot ulcers and, if these do not …

Diabetes, lower-extremity amputation, and death

O Hoffstad, N Mitra, J Walsh, DJ Margolis - Diabetes care, 2015 - Am Diabetes Assoc
OBJECTIVE The goal of the study was to determine whether complications of diabetes well-
known to be associated with death such as cardiovascular disease and renal failure fully …

Diabetic foot ulcers and vascular insufficiency: our population has changed, but our methods have not

DG Armstrong, K Cohen, S Courric… - Journal of diabetes …, 2011 - journals.sagepub.com
Diabetic foot complications are increasing in prevalence worldwide. Care and attention to
these complications have improved greatly. Many advanced therapies are now being …

Location, location, location: geographic clustering of lower-extremity amputation among Medicare beneficiaries with diabetes

DJ Margolis, O Hoffstad, J Nafash, CE Leonard… - Diabetes …, 2011 - Am Diabetes Assoc
OBJECTIVE Lower-extremity amputation (LEA) is common among persons with diabetes.
The goal of this study was to identify geographic variation and the influence of location on …

The metabolic syndrome and neuropathy: therapeutic challenges and opportunities

B Callaghan, E Feldman - Annals of neurology, 2013 - Wiley Online Library
The metabolic syndrome and neuropathy are common conditions, especially in the elderly,
that are associated with significant morbidity. Furthermore, the metabolic syndrome is …