BACKGROUND Many clinicians and patients believe that endometriosis-associated pain is
due to the lesions. Yet causality remains an enigma, because pain symptoms attributed to …

The brain responds differently to environmental and internal signals that relate to the stage
of development of neural systems. While genetic and epigenetic factors contribute to a …

This paper assesses the magnitude of Pb uptake in cortical and trabecular bones in healthy
animals and animals with altered balance in bone turnover, and the impact of exposure to …

This study tested the effects of ovariectomy, allied or not to high-fat feeding and estradiol
replacement, on hormonal, metabolic and behavioral parameters, to explore the connection …

Approximately 70% of male rats receiving severe T8 spinal contusions develop allodynia in
T5-7 dermatomes (at-level) beginning 2 weeks after injury. In contrast, rats having either …

Objectives High-velocity low-amplitude spinal manipulation (HVLA-SM), as performed by
doctors who use manual therapy (eg, doctors of chiropractic and osteopathy), results in …

The thalamus is a central structure important to modulating and processing all
mechanoreceptor input destined for the cortex. A large number of diverse mechanoreceptor …

Sexual function is a high priority quality of life issue among the spinal cord injury (SCI)
population. Over 12,000 new cases are reported in the USA annually, with males being …

Background Sex steroids have direct effects on the skeleton. Estrogen acts on the skeleton
via the classical genomic estrogen receptors alpha and beta (ERα and ERβ), a membrane …

Pain can vary over the estrous cycle as a result of changes in estradiol concentration but the
mechanism causing this variation is unclear. Because the thalamus is important in pain …