Glioblastoma multiforme (GBM) is one of the worst brain tumors arising from glial cells,
causing many deaths annually. Surgery, chemotherapy, radiotherapy and immunotherapy …

CXCL12 is a CXC chemokine that traditionally has been classified as a homeostatic
chemokine. It contributes to physiological processes such as embryogenesis, hematopoiesis …

Chemokines are small molecules called “chemotactic cytokines” and regulate many
processes like leukocyte trafficking, homing of immune cells, maturation, cytoskeletal …

Malignant tumors are characterized by structural and molecular peculiarities providing a
possibility to directionally deliver antitumor drugs with minimal impact on healthy tissues and …

Within the last decade, the introduction of checkpoint inhibitors proposed to boost the
patients' anti-tumor immune response has proven the efficacy of immunotherapeutic …

Simple Summary Chemokine signaling is crucial for tumorigenesis, proliferation,
angiogenesis, tumor progression and metastasis in glioblastoma. Furthermore, chemokines …

Although much effort has been dedicated to the development of efficient siRNA delivery for
cancer therapy, delivery nanomaterials that can particularly respond to reactive oxygen …

Co-delivery of chemotherapy drugs and VEGF siRNA (siVEGF) to control tumor growth has
been a research hotspot for improving cancer treatment. Current systems co-deliver siVEGF …

Cancer is a significant health hazard of the 21st century, and GLOBOCAN predicts
increasing cancer incidence in the coming decades. Though several conventional treatment …

Primary brain tumors are a leading cause of death worldwide and are characterized by
extraordinary heterogeneity and high invasiveness. Current drug and radiotherapy therapies …