Sleep deprivation and oxidative stress in animal models: a systematic review

G Villafuerte, A Miguel-Puga… - Oxidative medicine …, 2015 - Wiley Online Library
Because the function and mechanisms of sleep are partially clear, here we applied a meta‐
analysis to address the issue whether sleep function includes antioxidative properties in …

[HTML][HTML] Candidate mechanisms underlying the association between sleep-wake disruptions and Alzheimer's disease

J Cedernaes, RS Osorio, AW Varga, K Kam… - Sleep medicine …, 2017 - Elsevier
During wakefulness, extracellular levels of metabolites in the brain increase. These include
amyloid beta (Aβ), which contributes to the pathogenesis of Alzheimer's disease (AD) …

Exercise prevents sleep deprivation-associated anxiety-like behavior in rats: potential role of oxidative stress mechanisms

C Vollert, M Zagaar, I Hovatta, M Taneja, A Vu… - Behavioural brain …, 2011 - Elsevier
Our previous work suggests that pharmacological induction of oxidative stress causes
anxiety-like behavior in rats. Interestingly, sleep deprivation is reported to cause oxidative …

The neuroprotective effect of vitamin E on chronic sleep deprivation-induced memory impairment: the role of oxidative stress

KH Alzoubi, OF Khabour, BA Rashid, IM Damaj… - Behavioural Brain …, 2012 - Elsevier
Sleep deprivation induces oxidative stress and impairs learning and memory processes.
Vitamin E, on the other hand, is a strong antioxidant that has neuroprotective effect on the …

Sleep fragmentation induces cognitive deficits via nicotinamide adenine dinucleotide phosphate oxidase–dependent pathways in mouse

D Nair, SXL Zhang, V Ramesh, F Hakim… - American journal of …, 2011 - atsjournals.org
Rationale: Sleep fragmentation (SF) is one of the major characteristics of sleep apnea, and
has been implicated in its morbid consequences, which encompass excessive daytime …

The devastating effects of sleep deprivation on memory: lessons from rodent models

P Chen, W Ban, W Wang, Y You, Z Yang - Clocks & Sleep, 2023 - mdpi.com
In this narrative review article, we discuss the role of sleep deprivation (SD) in memory
processing in rodent models. Numerous studies have examined the effects of SD on …

Melatonin ameliorates cognitive impairment induced by sleep deprivation in rats: role of oxidative stress, BDNF and CaMKII

L Zhang, HQ Zhang, XY Liang, HF Zhang… - Behavioural brain …, 2013 - Elsevier
Sleep deprivation (SD) has been shown to induce oxidative stress which causes cognitive
impairment. Melatonin, an endogenous potent antioxidant, protects neurons from oxidative …

Short-term sleep deprivation leads to decreased systemic redox metabolites and altered epigenetic status

MS Trivedi, D Holger, AT Bui, TJA Craddock, JL Tartar - PloS one, 2017 - journals.plos.org
Sleep is critical for repair as well as the rejuvenation processes in the body and many of
these functions are regulated via underlying cellular metabolic homeostasis. Changes in …

Sericin protects against acute sleep deprivation-induced memory impairment via enhancement of hippocampal synaptic protein levels and inhibition of oxidative …

F Farajdokht, SM Vatandoust, L Hosseini, K Fekri… - Brain research …, 2021 - Elsevier
Sleep deprivation (SD) induces learning and memory deficits via inflammatory responses
and oxidative stress. On the other hand, sericin (Ser) possesses potent antioxidant and …

Human longevity is associated with regular sleep patterns, maintenance of slow wave sleep, and favorable lipid profile

DR Mazzotti, C Guindalini, WAS Moraes… - Frontiers in aging …, 2014 - frontiersin.org
Some individuals are able to successfully reach very old ages, reflecting higher adaptation
against age-associated effects. Sleep is one of the processes deeply affected by aging; …