Anti-Alzheimer's natural products derived from plant endophytic fungi

J Zhu, Z Wang, L Song, W Fu, L Liu - Molecules, 2023 - mdpi.com
Alzheimer's is the most common cause of dementia worldwide and seriously affects patients'
daily tasks. Plant endophytic fungi are known for providing novel and unique secondary …

Bioactive lipodepsipeptides produced by bacteria and fungi

A Evidente - International Journal of Molecular Sciences, 2022 - mdpi.com
Natural products are a vital source for agriculture, medicine, cosmetics and other fields.
Lipodepsipeptides (LPDs) are a wide group of natural products distributed among living …

Biosynthesis of cosmosporasides reveals the assembly line for fungal hybrid terpenoid saccharides

GY Yuan, JM Zhang, QD Xu, HR Zhang… - Angewandte …, 2023 - Wiley Online Library
Fungal hybrid terpenoid saccharides constitute a new and growing family of natural products
with significant biomedical and agricultural activities. One representative family is the …

The neuroprotective potential of endophytic fungi and proposed molecular mechanism: a current update

P Semwal, S Painuli, J Anand… - Evidence‐Based …, 2022 - Wiley Online Library
Millions of people are affected by neuronal disorders that are emerging as a principal cause
of death after cancer. Alzheimer's disease, ataxia, Parkinson's disease, multiple system …

Cytotoxic Cyclodepsipeptides and Cyclopentane Derivatives from a Plant-Associated Fungus Fusarium sp.

YJ Wang, CY Liu, YL Wang, FX Zhang… - Journal of Natural …, 2022 - ACS Publications
In this work, four new cyclodepsipeptides, fusarihexins C–E (1–3) and enniatin Q (4), four
new cyclopentane derivatives, fusarilins A–D (5–8), together with eight known compounds …

New Anti-Inflammatory β-Resorcylic Acid Lactones Derived from an Endophytic Fungus, Colletotrichum sp.

J Kim, JY Baek, S Bang, JY Kim, Y Jin, JW Lee… - ACS …, 2023 - ACS Publications
The endophytic fungus Colletotrichum gloeosprioides JS0419, isolated from the leaves of
the halophyte Suaeda japonica, produced four new β-resorcylic acid derivatives …

Fungal glycosides: Structure and biological function

H Hussain, NZ Mamadalieva, I Ali, IR Green… - Trends in Food Science …, 2021 - Elsevier
Background Natural products acquire vast and intriguing structural diversity and have been
recognized as a tremendously diverse source of new lead compounds. Numerous bioactive …

Endophytic fungi: a potential source for drugs against central nervous system disorders

A Pant, M Vasundhara - Brazilian Journal of Microbiology, 2023 - Springer
Neuroprotection is one of the important protection methods against neuronal cells and tissue
damage caused by neurodegenerative diseases such as Alzheimer's, Parkinson's …

Azaphilones from an Endophytic Penicillium sp. Prevent Neuronal Cell Death via Inhibition of MAPKs and Reduction of Bax/Bcl-2 Ratio

S Bang, JY Baek, GJ Kim, J Kim, SJ Kim… - Journal of Natural …, 2021 - ACS Publications
Fourteen azaphilone-type polyketides (1–14), including nine new ones (1–6 and 8–10),
were isolated from cultures of Vitex rotundifolia-associated Penicillium sp. JVF17, and their …

Spirocollequins A and B, new alkaloids featuring a spirocyclic isoindolinone core, from Colletotrichum boninense AM-12-2

NR Ariefta, T Koseki, Y Nishikawa, Y Shiono - Tetrahedron Letters, 2021 - Elsevier
A pair of new diastereomeric isoindolinone alkaloids, spirocollequins A and B, were isolated
from an endophytic fungus, Colletotrichum boninense AM-12-2. Their structures are …