Sex differences may play a critical role in modulating how chronic or heavy alcohol use
impacts the brain to cause the development of alcohol use disorder (AUD). AUD is a …

Stress and trauma exposure contribute to the development of psychiatric disorders such as
post-traumatic stress disorder (PTSD) and major depressive disorder (MDD) in a subset of …

Early-life stress (ELS) is thought to cause the development of visceral pain disorders. While
some individuals are vulnerable to visceral pain, others are resilient, but the intrinsic circuit …

Abstract Alcohol Use Disorder (AUD) is a leading cause of death and disability worldwide,
but current treatments are insufficient in fully addressing the symptoms that often lead to …

Alcohol use disorder (AUD) affects all sexes, however women who develop AUD may be
particularly susceptible to cravings and other components of the disease. While many brain …

Binge drinking that typically begins during adolescence can have long-lasting
neurobehavioral consequences, including alterations in the central and peripheral immune …

Alcohol use disorder (AUD) is associated with substantial morbidity, mortality, and societal
cost, and pharmacological treatment options are limited. The endogenous cannabinoid …

Alcohol drinking is often initiated during adolescence, and this frequently escalates to binge
drinking. As adolescence is also a period of dynamic neurodevelopment, preclinical …

Adolescent alcohol drinking is widely recognized as a significant public health problem, and
evidence is accumulating that sufficient levels of consumption during this critical period of …

Alcohol use and anxiety disorders occur in both males and females, but despite sharing
similar presentation and classical symptoms, the prevalence of alcohol use disorder (AUD) …