The cellular membrane constitutes one of the most fundamental compartments of a living
cell, where key processes such as selective transport of material and exchange of …

Abstract Purpose of Review Cholesteryl ester transfer proteins (CETP) regulate plasma
cholesterol levels by transferring cholesteryl esters (CEs) among lipoproteins. Lipoprotein …

Atherosclerosis is a major contributor to the onset and progression of cardiovascular
disease (CVD). Cholesterol‐loaded foam cells play a pivotal role in forming atherosclerotic …

Tubular lipid binding proteins (TULIPs) have become a focus of interest in the cell biology of
lipid signalling, lipid traffic and membrane contact sites. Each tubular domain has an internal …

Lipid transfer proteins (LTPs) transfer lipids between different organelles, and thus play key
roles in lipid homeostasis and organelle dynamics. The lipid transfer often occurs at the …

A lipid nanodisc is a discoidal lipid bilayer stabilized by proteins, peptides, or polymers on its
edge. Nanodiscs have two important connections to structural biology. The first is associated …

Peripheral membrane proteins (PMPs) bind temporarily to the surface of biological
membranes. They also exist in a soluble form and their tertiary structure is often known. Yet …

Cholesterol ester transfer protein (CETP) is important clinically and is one of the major
targets in cardiovascular disease studies. With high conformational flexibility, its tunnel …

Cholesteryl ester transfer protein (CETP) mediates the transfer of cholesteryl esters (CEs)
and triglycerides between different lipoproteins. Recent studies have shown that blocking …

Cholesteryl ester transfer protein (CETP) inhibitors are a new class of therapeutics for
dyslipidemia that simultaneously improve two major cardiovascular disease (CVD) risk …