Progresses in predicting post-translational modification
KC Chou - International Journal of Peptide Research and …, 2020 - Springer
Identification of the sites of post-translational modifications (PTMs) in protein, RNA, and DNA
sequences is currently a very hot topic. This is because the information thus obtained is very …
sequences is currently a very hot topic. This is because the information thus obtained is very …
[HTML][HTML] User-friendly and industry-integrated AI for medicinal chemists and pharmaceuticals
Artificial intelligence has brought crucial changes to the whole field of natural sciences.
Myriads of machine learning algorithms have been developed to facilitate the work of …
Myriads of machine learning algorithms have been developed to facilitate the work of …
Evaluating machine learning methodologies for identification of cancer driver genes
SJ Malebary, YD Khan - Scientific reports, 2021 - nature.com
Cancer is driven by distinctive sorts of changes and basic variations in genes. Recognizing
cancer driver genes is basic for accurate oncological analysis. Numerous methodologies to …
cancer driver genes is basic for accurate oncological analysis. Numerous methodologies to …
iGluK-Deep: computational identification of lysine glutarylation sites using deep neural networks with general pseudo amino acid compositions
Lysine glutarylation is a post-translation modification which plays an important regulatory
role in a variety of physiological and enzymatic processes including mitochondrial functions …
role in a variety of physiological and enzymatic processes including mitochondrial functions …
NPalmitoylDeep-PseAAC: A predictor of N-palmitoylation sites in proteins using deep representations of proteins and PseAAC via modified 5-steps rule
Background: Among all the major Post-translational modification, lipid modifications possess
special significance due to their widespread functional importance in eukaryotic cells. There …
special significance due to their widespread functional importance in eukaryotic cells. There …
iTSP-PseAAC: identifying tumor suppressor proteins by using fully connected neural network and PseAAC
Background: The uncontrolled growth due to accumulation of genetic and epigenetic
changes as a result of loss or reduction in the normal function of Tumor Suppressor Genes …
changes as a result of loss or reduction in the normal function of Tumor Suppressor Genes …
iPhosS (Deep)-PseAAC: Identification of Phosphoserine Sites in Proteins Using Deep Learning on General Pseudo Amino Acid Compositions
Among all the PTMs, the protein phosphorylation is pivotal for various pathological and
physiological processes. About 30 percent of eukaryotic proteins undergo the …
physiological processes. About 30 percent of eukaryotic proteins undergo the …
ProtoPred: advancing oncological research through identification of proto-oncogene proteins
SJ Malebary, R Khan, YD Khan - IEEE Access, 2021 - ieeexplore.ieee.org
Proto-oncogenes are the genes that have the potential to transform normal cells into cancer
cells as a result of mutations. They usually contain encoding of proteins whose function is to …
cells as a result of mutations. They usually contain encoding of proteins whose function is to …
Sequence-based identification of allergen proteins developed by integration of PseAAC and statistical moments via 5-step rule
YD Khan, E Alzahrani, W Alghamdi… - Current …, 2020 - ingentaconnect.com
Background: Allergens are antigens that can stimulate an atopic type I human
hypersensitivity reaction by an immunoglobulin E (IgE) reaction. Some proteins are naturally …
hypersensitivity reaction by an immunoglobulin E (IgE) reaction. Some proteins are naturally …
[HTML][HTML] iQSP: a sequence-based tool for the prediction and analysis of quorum sensing peptides via Chou's 5-steps rule and informative physicochemical properties
P Charoenkwan, N Schaduangrat… - … Journal of Molecular …, 2020 - ncbi.nlm.nih.gov
Understanding of quorum-sensing peptides (QSPs) in their functional mechanism plays an
essential role in finding new opportunities to combat bacterial infections by designing drugs …
essential role in finding new opportunities to combat bacterial infections by designing drugs …