The relationship between ABO blood group, von Willebrand factor, and primary hemostasis

SE Ward, JM O'Sullivan… - Blood, The Journal of the …, 2020 - ashpublications.org
Numerous studies have reported significant associations between ABO blood group and risk
of cardiovascular disease. These studies have consistently demonstrated that thrombotic …

Update on chronic thromboembolic pulmonary hypertension

IM Lang, M Madani - Circulation, 2014 - Am Heart Assoc
PEA. They might be classified as cases of chronic thromboembolic pulmonary vascular
disease. Although current practice in major centers is to perform exercise tests, there is still …

Genome partitioning of genetic variation for complex traits using common SNPs

J Yang, TA Manolio, LR Pasquale, E Boerwinkle… - Nature …, 2011 - nature.com
We estimate and partition genetic variation for height, body mass index (BMI), von
Willebrand factor and QT interval (QTi) using 586,898 SNPs genotyped on 11,586 unrelated …

Elevated factor VIII levels and risk of venous thrombosis

PV Jenkins, O Rawley, OP Smith… - British journal of …, 2012 - Wiley Online Library
Modern thrombophilia testing fails to identify any underlying prothrombotic tendency in a
significant number of patients presenting with objectively confirmed venous …

ABO blood group determines plasma von Willebrand factor levels: a biologic function after all?

PV Jenkins, JS O'Donnell - Transfusion, 2006 - Wiley Online Library
For many years, an association between ABO histo‐blood group and risk of thrombosis has
been recognized. Blood group non‐O (A, B, and AB) individuals have consistently been …

ABO blood group and risk of thromboembolic and arterial disease: a study of 1.5 million blood donors

SK Vasan, K Rostgaard, A Majeed, H Ullum… - Circulation, 2016 - Am Heart Assoc
Background—ABO blood groups have been shown to be associated with increased risks of
venous thromboembolic and arterial disease. However, the reported magnitude of this …

Common susceptibility alleles are unlikely to contribute as strongly as the FV and ABO loci to VTE risk: results from a GWAS approach

DA Trégouët, S Heath, N Saut… - Blood, The Journal …, 2009 - ashpublications.org
Venous thromboembolism (VTE) is a complex disease that has a major genetic component
of risk. To identify genetic factors that may modify the risk of VTE, we conducted a genome …

A shorter von Willebrand factor survival in O blood group subjects explains how ABO determinants influence plasma von Willebrand factor

L Gallinaro, MG Cattini, M Sztukowska… - Blood, The Journal …, 2008 - ashpublications.org
ABO blood groups greatly influence circulating von Willebrand factor (VWF) levels, and O
group subjects have lower VWF values. In this study, we investigated whether ABO groups …

Primary hemostatic capacity of whole blood: a comprehensive analysis of pathogen reduction and refrigeration effects over time

HF Pidcoke, SJ McFaul, AK Ramasubramanian… - …, 2013 - Wiley Online Library
Background Whole blood (WB) has been used in combat since World War I as it is readily
available and replaces every element of shed blood. Component therapy has become …

Relationship between ABO blood group and von Willebrand factor levels: from biology to clinical implications

M Franchini, F Capra, G Targher, M Montagnana… - Thrombosis journal, 2007 - Springer
Although a number of studies have demonstrated the influence of ABO blood group on
plasma levels of von Willebrand factor (VWF), the nature of this association and its clinical …