Post-stroke depression (PSD) is one of common and serious sequelae of stroke.
Approximately, one in three stroke survivors suffered from depression after stroke. It heavily …

Cytokines are pleiotropic molecules with important roles in inflammatory responses. Pro-
inflammatory cytokines and neuroinflammation are important not only in inflammatory …

Androgens and androgen receptors (AR) play a pivotal role in expression of the male
phenotype. Several diseases, such as androgen insensitivity syndrome (AIS) and prostate …

The occurrence of emerging organic pollutants (EOPs) in the aquatic environment
originating from point and diffuse sources, has been the subject of global apprehension in …

The secretion of glucocorticoids (GCs) is a classic endocrine response to stress. Despite
that, it remains controversial as to what purpose GCs serve at such times. One view …

Preterm birth occurs in 11% of live births globally and accounts for 35% of all newborn
deaths. Preterm newborns have immature immune systems, with reduced innate and …

The rat, mouse and human estrogen receptor (ER) exists as two subtypes, ERα and ERβ,
which differ in the C-terminal ligand-binding domain and in the N-terminal transactivation …

Ligand-dependent activation of transcription by nuclear receptors (NRs) is mediated by
interactions with coactivators. Receptor agonists promote coactivator binding, and …

Thyroid hormones (THs) play critical roles in the differentiation, growth, metabolism, and
physiological function of virtually all tissues. TH binds to receptors that are ligand …

Signs and symptoms that are characteristic for depression include changes in the setpoint of
the hypothalamic-pituitary-adrenocortical (HPA) system, which in the majority of these …