Aesculus hippocastanum in the pharmaceutical industry and beyond–Phytochemistry, bioactivity, present application, and future perspectives

A Owczarek-Januszkiewicz, A Kicel… - Industrial Crops and …, 2023 - Elsevier
Aesculus hippocastanum L.(horse-chestnut) is a widespread ornamental plant and an
essential medicinal species. Several valuable phytochemicals have been found in its …

Recent advances in synchrotron scattering methods for probing the structure and dynamics of colloids

T Narayanan - Advances in Colloid and Interface Science, 2024 - Elsevier
Recent progress in synchrotron based X-ray scattering methods applied to colloid science is
reviewed. An important figure of merit of these techniques is that they enable in situ …

pH effects on the molecular structure and charging state of β-Escin biosurfactants at the air-water interface

D Glikman, NG Rey, M Richert, K Meister… - Journal of Colloid and …, 2022 - Elsevier
Saponins like β-escin exhibit an unusually high surface activity paired with a remarkable
surface rheology which makes them as biosurfactants highly interesting for applications in …

[HTML][HTML] Characterization of size-tuneable aescin-lipid nanoparticles as platform for stabilization of membrane proteins

F Escobedo, M Gospalswamy, P Hägerbäumer… - Colloids and Surfaces B …, 2024 - Elsevier
Disc-like lipid nanoparticles stabilized by saponin biosurfactants display fascinating
properties, including their temperature-driven re-organization. β-Aescin, a saponin from …

Saponins form nonionic lipid nanodiscs for protein structural studies by Nuclear Magnetic Resonance Spectroscopy

SD McCalpin, T Ravula… - The journal of physical …, 2022 - ACS Publications
Structural studies of membrane proteins in native-like environments require the
development of diverse membrane mimetics. Currently there is a need for nanodiscs formed …

A simple method for continuous synthesis of bicelles in microfluidic systems

S Choi, B Kang, S Taguchi, H Umakoshi, K Kim… - Langmuir, 2021 - ACS Publications
Bicelle has great potential for drug delivery systems due to its small size and
biocompatibility. The conventional method of bicelle preparation contains a long process …

Recent advances in biosurfactant-based association colloids—self-assembly in water

T Hellweg, T Sottmann, J Oberdisse - Frontiers in Soft Matter, 2023 - frontiersin.org
Recent studies of self-assembly in binary systems of bio-surfactants, either of microbial
origin or saponins extracted from plants, are reviewed. Saponins in water reported in the first …

[HTML][HTML] Decomposition of mixed DMPC-aescin vesicles to bicelles is linked to the lipid's main phase transition: A direct evidence by using chain-deuterated lipid

C Dargel, LH Moleiro, A Radulescu, TJ Stank… - Journal of Colloid and …, 2025 - Elsevier
This work investigates the conversion of bicelles into larger sheets or closed vesicles upon
dilution and temperature increase for a system composed of the phospholipid 1, 2 …

Escin's phytochemistry and pharmacy: biosynthesis, chemistry, synergism and novel activities

S Fazliev, K Tursunov, A Sharipov, V Xaydarov… - Phytochemistry …, 2024 - Springer
Drug resistance against antibiotics and cancer chemotherapeutics are one of the pressing
issues before contemporary medicine. One way to overcome drug resistance …

Interactions between DMPC Model Membranes, the Drug Naproxen, and the Saponin β-Aescin

P Hägerbäumer, F Gräbitz-Bräuer, M Annegarn… - Pharmaceutics, 2023 - mdpi.com
In this study, the interplay among the phospholipid 1, 2-dimyristoyl-sn-glycero-3-
phosphocholine (DMPC) as a model membrane, the nonsteroidal anti-inflammatory drug …