The role of lncRNA-mediated ceRNA regulatory networks in pancreatic cancer

J Xu, J Xu, X Liu, J Jiang - Cell death discovery, 2022 - nature.com
Abstract Non-coding RNAs (ncRNAs), which occupy the vast majority of human transcripts
are known for their inability to encode proteins. NcRNAs consist of a diverse range of RNA …

[HTML][HTML] Curcumin: An epigenetic regulator and its application in cancer

T Ming, Q Tao, S Tang, H Zhao, H Yang, M Liu… - Biomedicine & …, 2022 - Elsevier
Nowadays, one of the leading causes of death in humans is cancer, which is still on the rise
globally and is in great need of intense study on the pathogenic mechanism and effective …

Applications of nanotechnologies for miRNA-based cancer therapeutics: current advances and future perspectives

LA Bravo-Vázquez, A Méndez-García… - … in Bioengineering and …, 2023 - frontiersin.org
MicroRNAs (miRNAs) are short (18–25 nt), non-coding, widely conserved RNA molecules
responsible for regulating gene expression via sequence-specific post-transcriptional …

Luteolin, a potent anticancer compound: from chemistry to cellular interactions and synergetic perspectives

H Singh Tuli, P Rath, A Chauhan, K Sak, D Aggarwal… - Cancers, 2022 - mdpi.com
Simple Summary Common flavonoid luteolin 3′, 4′, 5, 7-tetrahydroxyflavone has
immense potential to be utilized as a chemopreventive dietary molecule. According to …

The Regulatory Role of MicroRNAs in Obesity and Obesity-Derived Ailments

JA Benavides-Aguilar, A Torres-Copado… - Genes, 2023 - mdpi.com
Obesity is a condition that is characterized by the presence of excessive adipose tissue in
the body. Obesity has become one of the main health concerns worldwide since it can lead …

MicroRNA-mediated regulation of key signaling pathways in hepatocellular carcinoma: A mechanistic insight

LM Ruiz-Manriquez, O Carrasco-Morales… - Frontiers in …, 2022 - frontiersin.org
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer. The
molecular pathogenesis of HCC varies due to the different etiologies and genotoxic insults …

Functional implications and clinical potential of MicroRNAs in irritable bowel syndrome: a concise review

LA Bravo-Vázquez, I Medina-Ríos… - Digestive diseases and …, 2023 - Springer
Abstract MicroRNAs (miRNAs) are tiny (20–24 nucleotides long), non-coding, highly
conserved RNA molecules that play a crucial role within the post-transcriptional regulation of …

Exploring the potential role of circulating microRNAs as biomarkers for predicting clinical response to neoadjuvant therapy in breast cancer

LM Ruiz-Manriquez, C Villarreal-Garza… - International Journal of …, 2023 - mdpi.com
Breast cancer (BC) is a leading cause of cancer-related deaths among women worldwide.
Neoadjuvant therapy (NAT) is increasingly being used to reduce tumor burden prior to …

Thymoquinone potentially modulates the expression of key onco-and tumor suppressor miRNAs in prostate and colon cancer cell lines: Insights from PC3 and HCT-15 …

SM Osorio-Pérez, C Estrada-Meza, LM Ruiz-Manriquez… - Genes, 2023 - mdpi.com
Prostate cancer (PC) and colon cancer significantly contribute to global cancer-related
morbidity and mortality. Thymoquinone (TQ), a naturally occurring phytochemical found in …

Ginsenoside Rg3 alleviates cisplatin resistance of gastric cancer cells through inhibiting SOX2 and the PI3K/Akt/mTOR signaling Axis by up-regulating miR-429

X Wang, R He, L Geng, J Yuan, H Fan - Frontiers in Genetics, 2022 - frontiersin.org
Platinum-based cytotoxic chemotherapy is considered the standard treatment for advanced
gastric cancer (GC). However, cisplatin chemoresistance often occurs with the mechanisms …