Protein glycosylation in extracellular vesicles: Structural characterization and biological functions

J Macedo-da-Silva, VF Santiago… - Molecular …, 2021 - Elsevier
Extracellular vesicles (EVs) are lipid bilayer-enclosed particles involved in intercellular
communication, delivery of biomolecules from donor to recipient cells, cellular disposal and …

Glycomics and glycoproteomics: Approaches to address isomeric separation of glycans and glycopeptides

CD Gutierrez Reyes, P Jiang… - Journal of …, 2021 - Wiley Online Library
Abstract Changes in the glycome of human proteins and cells are associated with the
progression of multiple diseases such as Alzheimer's, diabetes mellitus, many types of …

Highly-sensitive label-free deep profiling of N-glycans released from biomedically-relevant samples

AL Marie, S Ray, AR Ivanov - Nature Communications, 2023 - nature.com
Alterations of protein glycosylation can serve as sensitive and specific disease biomarkers.
Labeling procedures for improved separation and detectability of oligosaccharides have …

Recent advances in the production, analysis, and application of galacto-oligosaccharides

MW Iqbal, T Riaz, S Mahmood, H Liaqat… - Food Reviews …, 2023 - Taylor & Francis
Galacto-oligosaccharides (GOS) are the prebiotic constituents with various functional
qualities that promote the optimal proliferation of gut microbiota and are consequently …

Clinical application of quantitative glycomics

W Peng, J Zhao, X Dong, A Banazadeh… - Expert review of …, 2018 - Taylor & Francis
Introduction: Aberrant glycosylation has been associated with many diseases. Decades of
research activities have reported many reliable glycan biomarkers of different diseases …

NEGATIVE ION MASS SPECTROMETRY FOR THE ANALYSIS OF N‐LINKED GLYCANS

DJ Harvey - Mass Spectrometry Reviews, 2020 - Wiley Online Library
N‐glycans from glycoproteins are complex, branched structures whose structural
determination presents many analytical problems. Mass spectrometry, usually conducted in …

MS-based glycomics: An analytical tool to assess nervous system diseases

W Peng, F Kobeissy, S Mondello, C Barsa… - Frontiers in …, 2022 - frontiersin.org
Neurological diseases affect millions of peopleochemistryorldwide and are continuously
increasing due to the globe's aging population. Such diseases affect the nervous system …

Prospects of pulsed amperometric detection in flow-based analytical systems-A review

MA Islam, P Mahbub, PN Nesterenko, B Paull… - Analytica chimica …, 2019 - Elsevier
Electrochemical (EC) detection techniques in flow-based analytical systems such as flow
injection analysis (FIA), capillary electrophoresis (CE), and liquid chromatography (LC) have …

High performance anion exchange and hydrophilic interaction liquid chromatography approaches for comprehensive mass spectrometry-based characterization of the …

Z Szabo, JR Thayer, D Reusch… - Journal of proteome …, 2018 - ACS Publications
Comprehensive characterization of the N-glycome of a therapeutic is challenging because
glycans may harbor numerous modifications (eg, phosphorylation, sulfation, sialic acids with …

Mass spectrometry-based qualitative and quantitative N-glycomics: An update of 2017–2018

K Xiao, Y Han, H Yang, H Lu, Z Tian - Analytica chimica acta, 2019 - Elsevier
N-glycosylation is one of the most frequently occurring protein post-translational
modifications (PTMs) with broad cellular, physiological and pathological relevance. Mass …