Innate and adaptive immunity during SARS-CoV-2 infection: biomolecular cellular markers and mechanisms
The coronavirus 2019 (COVID-19) pandemic was caused by a positive sense single-
stranded RNA (ssRNA) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
stranded RNA (ssRNA) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
An immunological review of SARS-CoV-2 infection and vaccine serology: innate and adaptive responses to mRNA, adenovirus, inactivated and protein subunit …
The coronavirus disease 2019 (COVID-19) pandemic is caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, which is defined by its positive …
respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, which is defined by its positive …
Direct detection of glycated human serum albumin and hyperglycosylated IgG3 in serum, by MALDI-ToF mass spectrometry, as a Predictor of COVID-19 severity
RK Iles, JK Iles, J Lacey, A Gardiner, R Zmuidinaite - Diagnostics, 2022 - mdpi.com
The prefusion spike protein of SARS-CoV-2 binds advanced glycation end product (AGE)-
glycated human serum albumin (HSA) and a higher mass (hyperglycosylated/glycated) …
glycated human serum albumin (HSA) and a higher mass (hyperglycosylated/glycated) …
[HTML][HTML] Navigating the Landscape of B Cell Mediated Immunity and Antibody Monitoring in SARS-CoV-2 Vaccine Efficacy: Tools, Strategies and Clinical Trial Insights
S O'Reilly, J Byrne, ER Feeney, PWG Mallon, V Gautier - Vaccines, 2024 - mdpi.com
Correlates of Protection (CoP) are biomarkers above a defined threshold that can replace
clinical outcomes as primary endpoints, predicting vaccine effectiveness to support the …
clinical outcomes as primary endpoints, predicting vaccine effectiveness to support the …
Antigen-Specific Antibody Signature Is Associated with COVID-19 Outcome
BB Salgado, MF Jordão, TBN de Morais, DSS da Silva… - Viruses, 2023 - mdpi.com
Numerous studies have focused on inflammation-related markers to understand COVID-19.
In this study, we performed a comparative analysis of spike (S) and nucleocapsid (N) protein …
In this study, we performed a comparative analysis of spike (S) and nucleocapsid (N) protein …
Cellular and Humoral Immunity and Infection Responses to SARS-CoV-2: Immune Biomolecular Mechanisms by Case Study within SARS-CoV-2 Pathogenesis and …
Abstract The coronavirus 2019 (COVID-19) pandemic was caused by a positive sense
single-stranded RNA (ssRNA) severe acute respiratory syndrome coronavirus 2 (SARS-CoV …
single-stranded RNA (ssRNA) severe acute respiratory syndrome coronavirus 2 (SARS-CoV …
The COVID-19 antibody responses, isotypes and glycosylation: Why SARS-CoV-2 Spike protein complex binding of IgG3 is potentiated in some and immuno …
RK Iles - medRxiv, 2023 - medrxiv.org
COVID-19 syndrome does not occur in all who are infected with SARS-CoV-2, and
symptoms vary. The anti-SARS CoV-2 Spike immune responses is confounded by the Spike …
symptoms vary. The anti-SARS CoV-2 Spike immune responses is confounded by the Spike …
Degree of immunoglobulin kappa light chain glycosylation of anti-spike SARS CoV-2 antibodies correlates with COVID-19 severity
R Grigaite, JK Iles, S Harding, R Patel, G Wallis, RK Iles - medRxiv, 2023 - medrxiv.org
Glycosylation of antibodies and the effects this has on inflammatory responses has
concentrated predominately on the study of glycosylation moieties found in the Fc region of …
concentrated predominately on the study of glycosylation moieties found in the Fc region of …
Validation of a MALDI-TOF MS Method for SARS-CoV-2 Detection on the Bruker Biotyper and Nasopharyngeal Swabs: A Brazil—UK Collaborative Study
OA Lovison, R Grigaitė, FCZ Volpato, JK Iles, J Lacey… - Diagnostics, 2023 - mdpi.com
We developed a MALDI-TOF mass spectrometry method for the detection of the SARS-CoV-
2 virus in saliva-gargle samples using Shimadzu MALDI-TOF mass spectrometers in the UK …
2 virus in saliva-gargle samples using Shimadzu MALDI-TOF mass spectrometers in the UK …
Direct detection of humoral marker corelates of COVID-19, glycated HSA and hyperglycosylated IgG3, by MALDI-ToF mass spectrometry
RK Iles, JK IIes, R Zmuidinaite, A Gardiner, J Lacey… - medRxiv, 2021 - medrxiv.org
The prefusion Spike protein of SARS-CoV2 binds advanced glycation end product (AGE)
glycated human serum albumin (HSA) and a higher mass, hyperglycosylated/glycated, IgG3 …
glycated human serum albumin (HSA) and a higher mass, hyperglycosylated/glycated, IgG3 …