Extracellular vesicles (EVs) are cell-derived membrane-enclosed particles that are involved
in physiologic and pathologic processes. EVs are increasingly being studied for therapeutic …

The past decade has witnessed an exponential increase in the number of publications
referring to extracellular vesicles (EVs). For many years considered to be extracellular …

Exosomes are small bilipid layer-enclosed extracellular vesicles that can be found in tissues
and biological fluids. As a key cell-to-cell and distant communication mediator, exosomes …

Exosomes are cell‐derived small extracellular vesicles that are naturally secreted by all
types of cells and widely distributed in various biofluids. They carry a variety of key bioactive …

Ischemic heart disease (IHD) is caused by the narrowing of arteries that work to provide
blood, nutrients, and oxygen to the myocardial tissue. The worldwide epidemic of IHD …

Recently, there has been growing interest in exosomal biomarkers for their active targeting
and specificity for delivering their cargos (proteins, lipids, nucleic acids) from the parent cell …

Exosomes are cup-shaped structures, made of two lipid layers. Their size is in the range of
30–150 nm. Exosomes are excreted to the extracellular space and function in local and …

Despite wide use of anti-vascular endothelial growth factor (VEGF) therapy for many solid
cancers, most individuals become resistant to this therapy, leading to disease progression …

MicroRNAs (miRNAs) have been shown to be critical mediators of many cellular and
developmental processes and have been implicated in different human diseases. Since the …

The crosstalk between tumor cells and the adjacent normal epithelium contributes to cancer
progression, but its regulators have remained elusive. Here, we show that breast cancer …