Role of artificial intelligence, machine learning and deep learning models in corneal disorders–A narrative review

B Gurnani, K Kaur, VG Lalgudi, G Kundu… - Journal Français d' …, 2024 - Elsevier
In the last decade, artificial intelligence (AI) has significantly impacted ophthalmology,
particularly in managing corneal diseases, a major reversible cause of blindness. This …

Current Advances in Corneal Stromal Stem Cell Biology and Therapeutic Applications

T Volatier, C Cursiefen, M Notara - Cells, 2024 - mdpi.com
Corneal stromal stem cells (CSSCs) are of particular interest in regenerative ophthalmology,
offering a new therapeutic target for corneal injuries and diseases. This review provides a …

Sertaconazole-PLGA nanoparticles for management of ocular keratitis

NE Eleraky, MA Attia, MA Safwat - Journal of Drug Delivery Science and …, 2024 - Elsevier
Ocular fungal infections can pose severe health conditions that may develop into vision
impairment and blindness. Sertaconazole (STZ) is a widely used antifungal; however, its low …

[HTML][HTML] Preclinical evaluation of the safety and effectiveness of a new bioartificial cornea

Y Hao, J Zhou, J Tan, F Xiang, Z Qin, J Yao, G Li… - Bioactive Materials, 2023 - Elsevier
Cross-linking agents are frequently used to restore corneal properties after decellularization,
and it is especially important to select an appropriate method to avoid excessive cross …

[HTML][HTML] Keratoconus

G Asimellis, EJ Kaufman - StatPearls [Internet], 2024 - ncbi.nlm.nih.gov
Keratoconus - StatPearls - NCBI Bookshelf US flag An official website of the United States
government Here's how you know NIH NLM Logo Access keys NCBI Homepage MyNCBI …

Greater exposure to PM2.5 and PM10 was associated with lower corneal nerve measures: the Maastricht study - a cross-sectional study

SBA Mokhtar, J Viljoen, CJH van der Kallen… - Environmental …, 2024 - Springer
Background Epidemiological and toxicological studies indicate that increased exposure to
air pollutants can lead to neurodegenerative diseases. To further confirm this relationship …

Keeping an eye on sustainable regeneration

MG Shibru, ZM Ali, S Alali, H Alkhoori… - Regenerative …, 2023 - Taylor & Francis
The shortage of viable organs for transplantation remains a significant problem in medical
practice. Among the various causes of blindness, corneal blindness ranks among the top …

[HTML][HTML] A bioengineered model for reinnervating the decellularized extracellular matrix of corneal scaffolds

ZF Murtaza, A Abou Fares, F AlMuhairi, J Paunovic… - Medical …, 2024 - Elsevier
Corneal diseases and injuries, with their substantial global prevalence and adverse effects
on quality of life, demographics, occupations, and lifestyles, pose a pressing healthcare …

Nanoemulsion-based pseudopolyrotaxane hydrogel for enhanced corneal bioavailability and treatment of corneal inflammation

G Fang, R Zhao, L Zhu, Q Wang, S Peng, L Kang… - Journal of Controlled …, 2025 - Elsevier
Corneal inflammation, a condition that can potentially lead to blindness, is often treated with
topical eye drops. However, the limited ocular drug bioavailability of the eye drops …

Integrated environmental and health economic assessments of novel xeno-keratografts addressing a growing public health crisis

M Ali, PR Corridon - Scientific Reports, 2024 - nature.com
Tissue scarcity poses global challenges for corneal transplantation and public health. Xeno-
keratoplasty using animal-derived tissues offers a potential solution, but its environmental …