The suicide death toll is alarmingly high, outnumbering deaths from war and homicide
worldwide (1). Many factors contribute to suicide death, making it difficult to prevent because …

Alcohol has been associated with violent crimes and domestic violence across many
nations. Various etiological factors were linked to chronic alcohol use and violence including …

Highlights•Stressful events during the perinatal period are associated with dysbiosis in the
offspring.•Stress in early life can impact the development and functioning of the …

Serotonin is a key neurotransmitter that is implicated in a wide variety of behavioral and
cognitive phenotypes. Originating in the raphe nuclei, 5-HT neurons project widely to …

Being different multifactorial forms of psychopathology, aggression, depression and suicidal
behavior, which is considered to be violent aggression directed against the self, have …

Depression has become one of the most prevalent neuropsychiatric disorders characterized
by anhedonia, anxiety, pessimism, or even suicidal thoughts. Receptor theory has been …

Major depressive disorder (MDD) is a complex psychiatric disease requiring
multidisciplinary approaches to identify specific risk factors and establish more efficacious …

Abstract Serotonin (5-hydroxytryptamine, 5-HT) is an intrinsically fluorescent
neurotransmitter found in organisms spanning a wide evolutionary range. Serotonin exerts …

Major depressive disorder (MDD) is a leading cause of disability, affecting more than 300
million people worldwide. We first review the well-known sex difference in incidence of …

Background Suicide is a global health crisis. However, no objective biomarkers of suicide
risk currently exist, and self-reported data can be unreliable, which limits prediction …