An exceptional safety profile has been shown in a large number of cell therapy clinical trials
that use mesenchymal stromal cells (MSCs). However, reliable potency assays are still …

The insufficient and unspecific target of traditional therapeutic approaches in cancer
treatment often leads to therapy resistance and cancer recurrence. Over the past decades …

Graft versus host disease (GvHD) is the clinical condition in which bone marrow-derived
mesenchymal stromal cells (MSCs) have been most frequently studied. In this review, we …

Tendon healing follows a complex series of coordinated events, which ultimately produces a
mechanically inferior tissue more scar-like than native tendon. More regenerative healing …

Human mesenchymal stem cells (MSCs) are considered to be a promising source of cells in
regenerative medicine. They have large potential to differentiate into various tissue-specific …

Background Graft-versus-host disease (GVHD) is a common fatal complication of
hematopoietic stem cell transplantation (HSCT), where steroids are used as a treatment …

This review summarizes the results of clinical trials of cell therapy in patients with heart
failure (HF). In contrast to acute myocardial infarction (where results have been consistently …

Perhaps the most important advance in the field of cell therapy for heart disease has been
the recognition that all stem/progenitor cells (both adult and embryonic) fail to engraft in the …

One of the exciting advances in modern medicine and life science is cell-based
neurovascular regeneration of damaged brain tissues and repair of neuronal structures. The …

The immunosuppressive activity of mesenchymal stromal cells (MSCs) in graft versus host
disease (GvHD) is well-documented, but their therapeutic benefit is rather unpredictable …