Over the past two decades, a convergence of basic and clinical evidence has established
the neuropeptide calcitonin-gene-related peptide (CGRP) as a key player in migraine …

Behavioral tests are very useful to understand the Neuro-psychotic disease and also helpful
in finding the treatment of the particular disease. Nowadays various tests are available to …

The neuropeptide calcitonin gene-related peptide (CGRP) plays a critical role in the
pathophysiology of migraine. We have focused on the role of CGRP in photophobia, which …

Migraine is a complex neurological disorder with a significant impact on patients and
society. Clinical and preclinical studies have established the neuropeptide calcitonin gene …

Background Polarization of microglia, the resident retinal immune cells, plays important
roles in mediating both injury and repair responses post-retinal ischemia–reperfusion (I/R) …

Photoallodynia (photophobia) occurs when normal levels of light cause pain ranging from
uncomfortable to debilitating. The only current treatment for photoallodynia is light …

Photopharmacological control of neuronal activity using synthetic photochromic ligands, or
photoswitches, is a promising approach for restoring visual function in patients suffering from …

The neuropeptide calcitonin gene-related peptide (CGRP) plays a key role in migraine.
However, a major challenge for studying CGRP actions is the lack of animal models for …

Melanopsin photoreception plays a vital role in irradiance detection for non-image forming
responses to light. However, little is known about the involvement of melanopsin in …

Migraine is a complex neurological disorder characterized by headache and sensory
abnormalities, such as hypersensitivity to light, observed as photophobia. Whilst it is …