The aryl hydrocarbon receptor and the gut–brain axis
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor initially
identified as the receptor for dioxin. Almost half a century after its discovery, AHR is now …
identified as the receptor for dioxin. Almost half a century after its discovery, AHR is now …
Targeting AhR as a novel therapeutic modality against inflammatory diseases
For decades, activation of Aryl Hydrocarbon Receptor (AhR) was excluded from
consideration as a therapeutic approach due to the potential toxic effects of AhR ligands and …
consideration as a therapeutic approach due to the potential toxic effects of AhR ligands and …
OVOL1 inhibits breast cancer cell invasion by enhancing the degradation of TGF-β type I receptor
Ovo-like transcriptional repressor 1 (OVOL1) is a key mediator of epithelial lineage
determination and mesenchymal–epithelial transition (MET). The cytokines transforming …
determination and mesenchymal–epithelial transition (MET). The cytokines transforming …
circSMARCA5 is an upstream regulator of the expression of miR-126-3p, miR-515-5p, and their mRNA targets, Insulin-like Growth Factor Binding Protein 2 (IGFBP2) …
AE Merulla, M Stella, C Barbagallo, R Battaglia… - International journal of …, 2022 - mdpi.com
The involvement of non-coding RNAs (ncRNAs) in glioblastoma multiforme (GBM)
pathogenesis and progression has been ascertained but their cross-talk within GBM cells …
pathogenesis and progression has been ascertained but their cross-talk within GBM cells …
The potential role of miR-124-3p in tumorigenesis and other related diseases
Q Li, S Liu, J Yan, MZ Sun, FT Greenaway - Molecular Biology Reports, 2021 - Springer
MicroRNAs (miRNAs) are a class of single‐stranded noncoding and endogenous RNA
molecules with a length of 18–25 nucleotides. Previous work has shown that miR-124-3p …
molecules with a length of 18–25 nucleotides. Previous work has shown that miR-124-3p …
Long non-coding RNA DLGAP1-AS1 promotes the progression of gastric cancer via miR-515-5p/MARK4 axis
L Li, Q Lai, M Zhang, J Jia - Brazilian Journal of Medical and …, 2021 - SciELO Brasil
Long non-coding RNA (lncRNA) is an essential regulator of carcinogenesis and cancer
progression. In the study, we explored the role of lncRNA DLGAP1-AS1 in gastric cancer …
progression. In the study, we explored the role of lncRNA DLGAP1-AS1 in gastric cancer …
[HTML][HTML] Deciphering the roles of aryl hydrocarbon receptor (AHR) in regulating carcinogenesis
Aryl hydrocarbon receptor (AHR) is a ligand-dependent receptor that belongs to the
superfamily of basic helix-loop-helix (bHLH) transcription factors. The activation of the …
superfamily of basic helix-loop-helix (bHLH) transcription factors. The activation of the …
The interplay of aryl hydrocarbon receptor/WNT/CTNNB1/Notch signaling pathways regulate amyloid beta precursor mRNA/protein expression and effected the …
M Keshavarzi, F Moradbeygi, K Mobini… - Toxicology …, 2022 - academic.oup.com
The amyloid beta precursor protein (APP) plays a pathophysiological role in the
development of Alzheimer's disease as well as a physiological role in neuronal growth and …
development of Alzheimer's disease as well as a physiological role in neuronal growth and …
Identification of estrogen receptor down-regulators for endocrine resistant breast cancer
Y Li, CM Orahoske, SM Urmetz, W Zhang… - The Journal of Steroid …, 2022 - Elsevier
Resistance to endocrine therapies remains an impediment for the treatment of estrogen
receptor (ER) positive breast cancer. ER down regulator Fulvestrant has showed great …
receptor (ER) positive breast cancer. ER down regulator Fulvestrant has showed great …
Disrupting Development: Unraveling the Interplay of Aryl Hydrocarbon Receptor (AHR) and Wnt/β-Catenin Pathways in Kidney Development Under the Influence of …
A Mohammadi-Bardbori, A Shadboorestan… - … Trace Element Research, 2024 - Springer
Understanding the intricate molecular mechanisms governing aryl hydrocarbon receptor
(AHR) and Wnt/β-Catenin pathways crosstalk is of paramount importance for elucidating …
(AHR) and Wnt/β-Catenin pathways crosstalk is of paramount importance for elucidating …