CRM1-mediated nuclear export: to the pore and beyond

S Hutten, RH Kehlenbach - Trends in cell biology, 2007 - cell.com
CRM1 (chromosome region maintenance 1; also referred to as exportin1 or Xpo1) is a
member of the importin β superfamily of nuclear transport receptors, recognizing proteins …

RNA Export through the NPC in Eukaryotes

M Okamura, H Inose, S Masuda - Genes, 2015 - mdpi.com
In eukaryotic cells, RNAs are transcribed in the nucleus and exported to the cytoplasm
through the nuclear pore complex. The RNA molecules that are exported from the nucleus …

New insights into nucleolar architecture and activity

I Raška, PJ Shaw, D Cmarko - International review of cytology, 2006 - Elsevier
The nucleolus is the most obvious and clearly differentiated nuclear subcompartment. It is
where ribosome biogenesis takes place and has been the subject of research over many …

Proteomic expression analysis of surgical human colorectal cancer tissues: up-regulation of PSB7, PRDX1, and SRP9 and hypoxic adaptation in cancer

J Rho, S Qin, JY Wang, MHA Roehrl - Journal of proteome …, 2008 - ACS Publications
Colorectal adenocarcinoma is one of the worldwide leading causes of cancer deaths.
Discovery of specific biomarkers for early detection of cancer progression and the …

Plasmodium falciparum signal recognition particle components and anti-parasitic effect of ivermectin in blocking nucleo-cytoplasmic shuttling of SRP

M Panchal, K Rawat, G Kumar, KM Kibria, S Singh… - Cell death & …, 2014 - nature.com
Signal recognition particle (SRP) is a ubiquitous ribonucleoprotein complex that targets
proteins to endoplasmic reticulum (ER) in eukaryotes. Here we report that Plasmodium …

Noncanonical functions and cellular dynamics of the mammalian signal recognition particle components

C Faoro, SF Ataide - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
The signal recognition particle (SRP) is a ribonucleoprotein complex fundamental for co-
translational delivery of proteins to their proper membrane localization and secretory …

A nonribosomal landscape in the nucleolus revealed by the stem cell protein nucleostemin

JCR Politz, I Polena, I Trask… - Molecular biology of …, 2005 - Am Soc Cell Biol
Nucleostemin is a p53-interactive cell cycle progression factor that shuttles between the
nucleolus and nucleoplasm, but it has no known involvement in ribosome synthesis. We …

The coming-of-age of nucleocytoplasmic transport in motor neuron disease and neurodegeneration

PA Ferreira - Cellular and Molecular Life Sciences, 2019 - Springer
The nuclear pore is the gatekeeper of nucleocytoplasmic transport and signaling through
which a vast flux of information is continuously exchanged between the nuclear and …

CRM1 and its ribosome export adaptor NMD3 localize to the nucleolus and affect rRNA synthesis

B Bai, HM Moore, M Laiho - Nucleus, 2013 - Taylor & Francis
CRM1 is an export factor that together with its adaptor NMD3 transports numerous cargo
molecules from the nucleus to cytoplasm through the nuclear pore. Previous studies have …

In vivo assembly of eukaryotic signal recognition particle: A still enigmatic process involving the SMN complex

S Massenet - Biochimie, 2019 - Elsevier
The signal recognition particle (SRP) is a universally conserved non-coding
ribonucleoprotein complex that is essential for targeting transmembrane and secretory …