Coronavirus belongs to the family of Coronaviridae, comprising single-stranded, positive-
sense RNA genome (+ ssRNA) of around 26 to 32 kilobases, and has been known to cause …

The main proteases (Mpro), also termed 3‐chymotrypsin‐like proteases (3CLpro), are a
class of highly conserved cysteine hydrolases in β‐coronaviruses. Increasing evidence has …

Long-term severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) shedding was
observed from the upper respiratory tract of a female immunocompromised individual with …

The US FDA approval of PAXLOVID, a combination therapy of nirmatrelvir and ritonavir has
significantly boosted our morale in fighting the COVID-19 pandemic. Nirmatrelvir is an …

The novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide. The main protease (M pro) of …

The coronavirus disease (COVID-19) pandemic has affected an estimated 16 million
persons and caused 0.6 million deaths worldwide by September 2020. The pandemic has …

The ongoing COVID-19 pandemic, caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) became a globally leading public health concern over the past …

The correlation between SARS-CoV-2 and oral manifestations is still controversial. The aim
of this observational study was to determine the oral manifestation of the hospitalized …

The lungs are the primary target of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) infection, with severe hypoxia being the cause of death in the most critical cases …

Respiratory virus challenge studies involve administration of the challenge virus and
sampling to assess for protection in the same anatomical locations. It can therefore be …