Discovering riboswitches: the past and the future

K Kavita, RR Breaker - Trends in biochemical sciences, 2023 - cell.com
Riboswitches are structured noncoding RNA domains used by many bacteria to monitor the
concentrations of target ligands and regulate gene expression accordingly. In the past 20 …

[图书][B] RNA, the epicenter of genetic information

J Mattick, P Amaral - 2023 - library.oapen.org
The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Riboswitches as drug targets for antibiotics

V Panchal, R Brenk - Antibiotics, 2021 - mdpi.com
Riboswitches reside in the untranslated region of RNA and regulate genes involved in the
biosynthesis of essential metabolites through binding of small molecules. Since their …

Aptamers, Riboswitches, and Ribozymes in S. cerevisiae Synthetic Biology

H Ge, MA Marchisio - Life, 2021 - mdpi.com
Among noncoding RNA sequences, riboswitches and ribozymes have attracted the attention
of the synthetic biology community as circuit components for translation regulation. When …

The occurrence and function of alternative splicing in fungi

S Fang, X Hou, K Qiu, R He, X Feng, X Liang - Fungal Biology Reviews, 2020 - Elsevier
Alternative splicing is a common but complex posttranscriptional regulatory process in
eukaryotes, through which multiple different transcripts are produced from a single pre …

Intrinsic regulatory role of RNA structural arrangement in alternative splicing control

K Taylor, K Sobczak - International journal of molecular sciences, 2020 - mdpi.com
Alternative splicing is a highly sophisticated process, playing a significant role in
posttranscriptional gene expression and underlying the diversity and complexity of …

Thiamine metabolism genes in diatoms are not regulated by thiamine despite the presence of predicted riboswitches

M Llavero‐Pasquina, K Geisler, A Holzer… - New …, 2022 - Wiley Online Library
Thiamine pyrophosphate (TPP), an essential co‐factor for all species, is biosynthesised
through a metabolically expensive pathway regulated by TPP riboswitches in bacteria, fungi …

To each their own: Delving into the vitaminic preferences of non-Saccharomyces wine yeasts

MS Evers, L Ramousse, C Morge, C Sparrow… - Food …, 2023 - Elsevier
Considering the growing interest in non-Saccharomyces wine yeasts, and notably in the
context of mixed fermentations with S. cerevisiae, understanding their nutritional behaviors …

Engineering CRISPR guide RNA riboswitches for in vivo applications

R Galizi, A Jaramillo - Current opinion in biotechnology, 2019 - Elsevier
Highlights•Riboswitches and CRISPR-editing challenges, current and future applications.•
Riboswitches can be applied to sense CRISPR-sgRNAs.•CRISPR gRNA riboswitches can …

Exploring the structure, function of thiamine pyrophosphate riboswitch, and designing small molecules for antibacterial activity

PD Wakchaure, B Ganguly - Wiley Interdisciplinary Reviews …, 2023 - Wiley Online Library
During the last decade, riboswitches emerged as new small‐molecule sensing RNA in
bacteria. Thiamine pyrophosphate (TPP) riboswitch is widely distributed and occurs in …