Pseudomonas aeruginosa is an opportunistic pathogen affecting immunocompromised
patients. It is known as the leading cause of morbidity and mortality in cystic fibrosis (CF) …

Pseudomonas aeruginosa is an opportunistic pathogen and the leading cause of mortality
among immunocompromised patients in clinical setups. The hallmarks of virulence in P …

Transition metals occupy an essential niche in biological systems. Their electrostatic
properties stabilize substrates or reaction intermediates in the active sites of enzymes, and …

Changes in the microbial community structure are observed in individuals with intestinal
inflammatory disorders. These changes are often characterized by a depletion of obligate …

Chronic Pseudomonas aeruginosa infections cause significant morbidity in patients with
cystic fibrosis (CF). Over years to decades, P. aeruginosa adapts genetically as it …

SUMMARY A select group of microorganisms inhabit the airways of individuals with cystic
fibrosis. Once established within the pulmonary environment in these patients, many of …

It is interesting to speculate that the evolutionary drive for microbes to develop pathogenic
characteristics was to access the nutrient resources that animals provided. Animal …

Chronic respiratory diseases including chronic rhinosinusitis, otitis media, asthma, cystic
fibrosis, non-CF bronchiectasis, and chronic obstructive pulmonary disease are a major …

It is generally assumed that antibiotics and resistance determinants are the task forces of a
biological warfare in which each resistance determinant counteracts the activity of a specific …

Microbes have shown a remarkable ability in evading the killing actions of antimicrobial
agents, such that treatment of bacterial infections represents once more an urgent global …