Hyperglycemia associated metabolic and molecular alterations in cancer risk, progression, treatment, and mortality

P Ramteke, A Deb, V Shepal, MK Bhat - Cancers, 2019 - mdpi.com
Cancer and diabetes are amongst the leading causes of deaths worldwide. There is an
alarming rise in cancer incidences and mortality, with approximately 18.1 million new cases …

Association of DNA repair gene polymorphisms with colorectal cancer risk and treatment outcomes

FN Al-Shaheri, KM Al-Shami, EH Gamal… - … and molecular pathology, 2020 - Elsevier
Colorectal cancer (CRC) is the third most common carcinoma worldwide. Despite the
progress in screening and treatment, CRC remains a leading cause of cancer-related …

DNA repair genes in astrocytoma tumorigenesis, progression and therapy resistance

JF Sousa, RB Serafim, LM Freitas… - … and Molecular Biology, 2019 - SciELO Brasil
Glioblastoma (GBM) is the most common and malignant type of primary brain tumor,
showing rapid development and resistance to therapies. On average, patients survive 14.6 …

Baicalin attenuates XRCC1-mediated DNA repair to enhance the sensitivity of lung cancer cells to cisplatin

Z Yin, E Chen, X Cai, E Gong, Y Li, C Xu… - Journal of Receptors …, 2022 - Taylor & Francis
Baicalin plays important roles in different types of cancer. A previous report showed that
baicalin attenuates cisplatin resistance in lung cancer. However, its mechanism remains …

The contribution of XRCC3 genotypes to childhood acute lymphoblastic leukemia

JS Pei, WS Chang, PC Hsu, CC Chen… - Cancer Management …, 2018 - Taylor & Francis
Purpose A growing body of evidence shows an association between DNA repair protein
genotypes and susceptibility to various cancers. However, few studies have assessed the …

Gene polymorphism in DNA repair genes XRCC 1 and XRCC 6 and association with colorectal cancer in Swedish patients

J Dimberg, M Skarstedt, R Slind Olsen, RE Andersson… - Apmis, 2016 - Wiley Online Library
The DNA repair genes XRCC 1 and XRCC 6 have been proposed to participate in the
pathological process of cancer by modulating the DNA repair capacity. This study evaluated …

XRCC3 Thr241Met gene polymorphism and risk of colorectal cancer in Kashmir: a case control study

S Nissar, AS Sameer, TA Lone… - Asian Pacific Journal …, 2014 - koreascience.kr
XRCC (X-ray cross-complementing group) genes contribute to important DNA repair
mechanisms that play roles in the repair of single strand breaks (SSBs) induced by a variety …

Genetic variants of XRCC1 and risk of hepatocellular carcinoma in chronic hepatitis C patients

M Arafa, T Besheer, AM El-Eraky… - British Journal of …, 2019 - Taylor & Francis
ABSTRACT Background: Hepatitis C virus (HCV) related liver cirrhosis occurs in about 20%
of chronically infected patients over a duration of 10–20 years, and within 5 years …

Colorectal cancer and genetic polymorphism in key regulatory low penetrance genes

MZ Banday, AS Sameer, S Nissar - Genetic Polymorphism and cancer …, 2021 - Springer
Colorectal cancer (CRC) is one of the major solid tissue malignancies affecting the
worldwide population. CRC is the third most common cancer and fourth among the major …

XRCC1 R399Q polymorphism and colorectal cancer risk in the Chinese Han population: a meta-analysis

CJ Qin, KW Xu, ZH Chen, ET Zhai, YL He, XM Song - Tumor Biology, 2015 - Springer
X-ray repair cross-complementing group 1 (XRCC1) plays a key role in DNA repair, genetic
instability, and tumorigenesis. The XRCC1 R399Q polymorphism has been reported in …