Rapidly progressive dementias—aetiologies, diagnosis and management
Rapidly progressive dementias (RPDs) are a group of heterogeneous disorders that include
immune-mediated, infectious and metabolic encephalopathies, as well as prion diseases …
immune-mediated, infectious and metabolic encephalopathies, as well as prion diseases …
Paraneoplastic neurological syndromes in the era of immune-checkpoint inhibitors
F Graus, J Dalmau - Nature Reviews Clinical Oncology, 2019 - nature.com
Paraneoplastic neurological syndromes (PNSs) comprise a group of disorders that can
affect any part of the nervous system in patients with cancer and frequently result from …
affect any part of the nervous system in patients with cancer and frequently result from …
Small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up☆
AMC Dingemans, M Früh, A Ardizzoni… - Annals of …, 2021 - annalsofoncology.org
Small-cell lung cancer (SCLC) is the most aggressive form of lung cancer. Although SCLC is
characterised by rapid responses to chemotherapy (ChT) and sensitivity to radiotherapy …
characterised by rapid responses to chemotherapy (ChT) and sensitivity to radiotherapy …
Neurologic complications of immune checkpoint inhibitors
AM Haugh, JC Probasco… - Expert opinion on drug …, 2020 - Taylor & Francis
Introduction: Immune checkpoint inhibitors (ICI) are associated with a wide spectrum of
neurologic immune-related adverse events (irAEs) including meningo-encephalitis …
neurologic immune-related adverse events (irAEs) including meningo-encephalitis …
Peripheral neuropathies
R Hanewinckel, MA Ikram, PA Van Doorn - Handbook of clinical neurology, 2016 - Elsevier
Peripheral neuropathies are diseases of the peripheral nervous system that can be divided
into mononeuropathies, multifocal neuropathies, and polyneuropathies. Symptoms usually …
into mononeuropathies, multifocal neuropathies, and polyneuropathies. Symptoms usually …
Paraneoplastic neurologic disorders
M Gilligan, C McGuigan, A McKeon - Current neurology and neuroscience …, 2023 - Springer
Abstract Purpose of Review To provide an overview and highlight recent updates in the field
of paraneoplastic neurologic disorders. Recent Findings The prevalence of paraneoplastic …
of paraneoplastic neurologic disorders. Recent Findings The prevalence of paraneoplastic …
[HTML][HTML] Outcome and biomarker analysis from a multicenter phase 2 study of ipilimumab in combination with carboplatin and etoposide as first-line therapy for …
Objectives Our aim was to evaluate the safety and efficacy of ipilimumab combined with
standard first-line chemotherapy for patients with extensive-stage SCLC. Methods Patients …
standard first-line chemotherapy for patients with extensive-stage SCLC. Methods Patients …
CTLA4 blockade elicits paraneoplastic neurological disease in a mouse model
LM Yshii, CM Gebauer, B Pignolet, E Maure… - Brain, 2016 - academic.oup.com
CTLA4 is an inhibitory regulator of immune responses. Therapeutic CTLA4 blockade
enhances T cell responses against cancer and provides striking clinical results against …
enhances T cell responses against cancer and provides striking clinical results against …
The immunobiology of autoimmune encephalitides
H Alexopoulos, MC Dalakas - Journal of Autoimmunity, 2019 - Elsevier
Autoimmune encephalitides, with an estimated incidence of 1.5 per million population per
year, although described only 15 years ago, have already had a remarkable impact in …
year, although described only 15 years ago, have already had a remarkable impact in …
[HTML][HTML] Paraneoplastic syndromes in small cell lung cancer
Paraneoplastic syndromes can commonly occur due to lung cancer, especially small cell
lung cancer. Frequently paraneoplastic syndromes can precede the diagnosis of the …
lung cancer. Frequently paraneoplastic syndromes can precede the diagnosis of the …