Diastereoselective Formal 1, 3-Dipolar Cycloaddition of Trifluoroethyl Amine-Derived Ketimines Enables the Desymmetrization of Cyclopentenediones

LQ Li, JQ Zhao, YP Zhang, Y You, ZH Wang, ZZ Ge… - Molecules, 2023 - mdpi.com
In this research, a metal-free diastereoselective formal 1, 3-dipolar cycloaddition of N-2, 2, 2-
trifluoroethylisatin ketimines and cyclopentene-1, 3-diones which can efficiently lead to the …

Spirocyclization and Michael addition of 3-benzylidene succinimides: route to spirocyclopentapyrrolidine-tetraones and benzylidene N-arylpyrrolidine-diones

P Dahiya, A Yadav, RK Peddinti - Organic & Biomolecular Chemistry, 2023 - pubs.rsc.org
Reactions of 3-benzylidene succinimides with 2-substituted 2-hydroxy-indane-1, 3-diones
and unsaturated pyrazolones are carried out under basic conditions to afford spirocyclized …

Silver‐Catalyzed Asymmetric Double Desymmetrization via Vinylogous Michael Addition of Prochiral α, α‐Dicyanoalkenes to Cyclopentendiones

K Choudhary, H Joshi, S Rohilla… - Chemistry–A European …, 2024 - Wiley Online Library
An asymmetric double desymmetrization methodology has been developed for synthesizing
densely functionalized chiral cyclopentylcyclohexane scaffolds. We have constructed four …

Organocatalyzed Modular Synthesis of Polycyclic Dihydropyridines and Pyridines through Sulfamate Linchpin

V Bhajammanavar, P Sureshbabu… - Chemistry–An Asian …, 2022 - Wiley Online Library
The cascade annulation between alkylidene malononitriles and cyclic sulfamidate imines
has been controlled by leveraging the sulfamate functionality under organocatalysis, which …