[HTML][HTML] Endometriosis: where are we and where are we going?

AD Greene, SA Lang, JA Kendziorski… - Reproduction …, 2016 - ncbi.nlm.nih.gov
Endometriosis currently affects∼ 5.5 million reproductive-aged women in the US with
symptoms such as painful periods (dysmenorrhea), chronic pelvic pain, pain with …

Endometriosis, a disease of the macrophage

A Capobianco, P Rovere-Querini - Frontiers in immunology, 2013 - frontiersin.org
Endometriosis, a common cause of pelvic pain and female infertility, depends on the growth
of vascularized endometrial tissue at ectopic sites. Endometrial fragments reach the …

Endometriosis: current challenges in modeling a multifactorial disease of unknown etiology

H Malvezzi, EB Marengo, S Podgaec… - Journal of Translational …, 2020 - Springer
Endometriosis is a chronic inflammatory hormone-dependent condition associated with
pelvic pain and infertility, characterized by the growth of ectopic endometrium outside the …

The selective vitamin D receptor agonist, elocalcitol, reduces endometriosis development in a mouse model by inhibiting peritoneal inflammation

M Mariani, P Vigano, D Gentilini, B Camisa… - Human …, 2012 - academic.oup.com
BACKGROUND Endometriosis, which is characterized by the growth of endometrial tissue at
ectopic locations as well as vascular development and inflammation, is still an unmet clinical …

Organ-on-a-chip: future of female reproductive pathophysiological models

ZM Deng, FF Dai, RQ Wang, HB Deng, TL Yin… - Journal of …, 2024 - Springer
The female reproductive system comprises the internal and external genitalia, which
communicate through intricate endocrine pathways. Besides secreting hormones that …

Diminished Ovarian Reserve in Endometriosis: Insights from In Vitro, In Vivo, and Human Studies—A Systematic Review

Z Tan, X Gong, CC Wang, T Zhang… - International Journal of …, 2023 - mdpi.com
Endometriosis, a prevalent disorder in women of reproductive age, is often associated with
undesired infertility. Ovarian reserve, an essential measure of ovarian function that is crucial …

Nonsurgical mouse model of endometriosis-associated pain that responds to clinically active drugs

V Fattori, NS Franklin, R Gonzalez-Cano, D Peterse… - Pain, 2020 - journals.lww.com
2.1. Study design Our objective was to standardize a nonsurgical mouse model of
endometriosis-associated pain. Our strategy was to interrogate both spontaneous and …

[HTML][HTML] The elusive and controversial roles of estrogen and progesterone receptors in human endometriosis

R Shao, S Cao, X Wang, Y Feng… - American journal of …, 2014 - ncbi.nlm.nih.gov
Endometriosis is a complex and challenging disease that involves aberrant adhesion,
growth, and progression of endometrial tissues outside of the uterine cavity, and there is …

Omega-3 polyunsaturated fatty acids suppress the cystic lesion formation of peritoneal endometriosis in transgenic mouse models

K Tomio, K Kawana, A Taguchi, Y Isobe, R Iwamoto… - PloS one, 2013 - journals.plos.org
Omega-3 polyunsaturated fatty acids (omega-3 PUFAs) play a role in controlling
pathological inflammatory reactions. Endometriosis is characterized by the presence of …

MCP-1 exerts the inflammatory response via ILK activation during endometriosis pathogenesis

UK Soni, R Tripathi, RK Jha - Life Sciences, 2024 - Elsevier
Aims MCP-1 has been shown to be elevated in endometriosis. ILK functions in several
cellular events and interacts with MCP-1-signaling. In the current study, we evaluated the …