Comparative oncology clinical trials play an important and growing role in cancer research
and drug development efforts. These trials, typically conducted in companion (pet) dogs …

Behavioral genetics in dogs has focused on modern breeds, which are isolated subgroups
with distinctive physical and, purportedly, behavioral characteristics. We interrogated breed …

Many dogs and cats are affected by chronic diseases that significantly impact their health
and welfare and relationships with humans. Some of these diseases can be challenging to …

Abstract Background The international Dog10K project aims to sequence and analyze
several thousand canine genomes. Incorporating 20× data from 1987 individuals, including …

Abstract We present GSD_1. 0, a high-quality domestic dog reference genome with
chromosome length scaffolds and contiguity increased 55-fold over CanFam3. 1. Annotation …

Dogs have become a valuable model in exploring multifaceted diseases and biology
relevant to human health. Despite large-scale dog genome projects producing high-quality …

Advances in DNA sequencing and other technologies have greatly facilitated the
identification of genetic risk factors for inherited diseases in dogs. We review recent …

Histiocytic sarcoma is an aggressive hematopoietic malignancy of mature tissue histiocytes
with a poorly understood etiology in humans. A histologically and clinically similar …

Canine atopic dermatitis is an inflammatory skin disease with clinical similarities to human
atopic dermatitis. Several dog breeds are at increased risk for developing this disease but …

Biobanking refers to the systematic collection, storage, and distribution of pre-or post-
mortem biological samples derived from volunteer donors. The demand for high-quality …