Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the American Heart Association/American Stroke …
Background and Purpose—This scientific statement provides an overview of the evidence
on vascular contributions to cognitive impairment and dementia. Vascular contributions to …
on vascular contributions to cognitive impairment and dementia. Vascular contributions to …
Disordered APP metabolism and neurovasculature in trauma and aging: combined risks for chronic neurodegenerative disorders
MD Ikonomovic, Z Mi, EE Abrahamson - Ageing research reviews, 2017 - Elsevier
Traumatic brain injury (TBI), advanced age, and cerebral vascular disease are factors
conferring increased risk for late onset Alzheimer's disease (AD). These conditions are also …
conferring increased risk for late onset Alzheimer's disease (AD). These conditions are also …
Identification of age-and gender-associated long noncoding RNAs in the human brain with Alzheimer's disease
Alzheimer's disease (AD) is an age-and gender-associated brain disorder. Long noncoding
RNAs (lncRNAs) have emerged as key regulators of brain development, homeostasis, and …
RNAs (lncRNAs) have emerged as key regulators of brain development, homeostasis, and …
[HTML][HTML] The nuclear retention of transcription factor FOXO3a correlates with a DNA damage response and increased glutamine synthetase expression by astrocytes …
The accumulation of reactive oxygen species leading to oxidative damage and cell death
plays an important role in a number of neurodegenerative disorders. FOXO3a, the main …
plays an important role in a number of neurodegenerative disorders. FOXO3a, the main …
DNA-dependent protein kinase and DNA repair: relevance to Alzheimer's disease
J Kanungo - Alzheimer's research & therapy, 2013 - Springer
The pathological hallmark of Alzheimer's disease (AD), the leading cause of senile
dementia, involves region-specific neuronal death and an accumulation of neuronal and …
dementia, involves region-specific neuronal death and an accumulation of neuronal and …
Relationships between the amyloid precursor protein and its various proteolytic fragments and neuronal systems
S Hunter, C Brayne - Alzheimer's Research & Therapy, 2012 - Springer
Alzheimer's disease (AD) is a progressive neurodegenerative disease and in its familial form
is associated with mutations in the amyloid precursor protein (APP) and the presenilins …
is associated with mutations in the amyloid precursor protein (APP) and the presenilins …
Human adipose tissue-derived multilineage progenitor cells exposed to oxidative stress induce neurite outgrowth in PC12 cells through p38 MAPK signaling
M Moriyama, H Moriyama, A Ueda, Y Nishibata… - BMC Cell Biology, 2012 - Springer
Background Adipose tissues contain populations of pluripotent mesenchymal stem cells that
also secrete various cytokines and growth factors to support repair of damaged tissues. In …
also secrete various cytokines and growth factors to support repair of damaged tissues. In …