Age‐related macular degeneration: new paradigms for treatment and management of AMD

LF Hernández-Zimbrón… - Oxidative medicine …, 2018 - Wiley Online Library
Age‐related macular degeneration (AMD) is a well‐characterized and extensively studied
disease. It is currently considered the leading cause of visual disability among patients over …

Stem cell based therapies for age-related macular degeneration: the promises and the challenges

H Nazari, L Zhang, D Zhu, GJ Chader… - Progress in retinal and …, 2015 - Elsevier
Age-related macular degeneration (AMD) is the leading cause of blindness among the
elderly in developed countries. AMD is classified as either neovascular (NV-AMD) or non …

Current therapeutic developments in atrophic age-related macular degeneration

J Hanus, F Zhao, S Wang - British Journal of Ophthalmology, 2016 - bjo.bmj.com
Age-related macular degeneration (AMD), a degenerative disorder of the central retina, is
the leading cause of irreversible blindness in the elderly. The underlying mechanism of the …

[HTML][HTML] Recent advances in the management of dry age-related macular degeneration: a review

F Bandello, R Sacconi, L Querques, E Corbelli… - …, 2017 - ncbi.nlm.nih.gov
Age-related macular degeneration (AMD), the most important cause of vision loss in elderly
people, is a degenerative disorder of the central retina with a multifactorial etiopathology …

A review of current and future management of geographic atrophy

R Sacconi, E Corbelli, L Querques, F Bandello… - Ophthalmology and …, 2017 - Springer
Age-related macular degeneration (AMD) is a multifactorial disease and a leading cause of
vision impairment in elderly people in Western society. Geographic atrophy (GA), the late …

A review of the emerging role of silk for the treatment of the eye

SH Tran, CG Wilson, FP Seib - Pharmaceutical research, 2018 - Springer
Silk is a remarkable biopolymer with a long history of medical use. Silk fabrications have a
robust track record for load-bearing applications, including surgical threads and meshes …

Directing differentiation of pluripotent stem cells toward retinal pigment epithelium lineage

P Choudhary, H Booth, A Gutteridge… - Stem Cells …, 2017 - academic.oup.com
Abstract Development of efficient and reproducible conditions for directed differentiation of
pluripotent stem cells into specific cell types is important not only to understand early human …

Emerging treatment options for geographic atrophy (GA) secondary to age-related macular degeneration

H Khan, AA Aziz, H Sulahria, H Khan… - Clinical …, 2023 - Taylor & Francis
Age-related macular degeneration (AMD) is characterized as a chronic, multifactorial
disease and is the leading cause of irreversible blindness. Advanced AMD is classified as …

Concise review: making stem cells retinal: methods for deriving retinal pigment epithelium and implications for patients with ocular disease

LL Leach, DO Clegg - Stem Cells, 2015 - academic.oup.com
Stem cells provide a potentially unlimited source of cells for treating a plethora of human
diseases. Regenerative therapies for retinal degenerative diseases are at the forefront of …

Induced pluripotent stem cell-based therapy for age-related macular degeneration

P Bracha, NA Moore, TA Ciulla - Expert Opinion on Biological …, 2017 - Taylor & Francis
Introduction: In age-related macular degeneration (AMD), stem cells could possibly replace
or regenerate disrupted pathologic retinal pigment epithelium (RPE), and produce …